Ying Hu1, Peishan Lu1, Xiuying Deng1, Hongxiong Guo2, Minghao Zhou3. 1. The Department of Expanded Program on Immunization, Jiangsu Provincial Center for Disease Prevention and Control, 172 Jiangsu Road, Nanjing, 210009, China. 2. The Department of Expanded Program on Immunization, Jiangsu Provincial Center for Disease Prevention and Control, 172 Jiangsu Road, Nanjing, 210009, China. guohongxiong@jscdc.cn. 3. The Department of Expanded Program on Immunization, Jiangsu Provincial Center for Disease Prevention and Control, 172 Jiangsu Road, Nanjing, 210009, China. zmh@jscdc.cn.
Abstract
BACKGROUND: To eliminate measles, the coverage of more than 90% vaccine is required in China. Nonetheless, the measles incidence still reached to 3.88 per 100,000 in 2014, which is far more than the target of 1 per 1,000,000. Moreover, there is little national surveillance to measles antibody level indicating herd immunity status in China. METHODS: We detected the level of antibody to measles using commercially available indirect enzyme-linked immunosorbent IgG assays, and calculated the protection rate of population (PRP) to measles virus infection among health peoples in China. RESULTS: During the years 2009-2015, among the Chinese population aged 0-56, PRP was 94.7, 91.6, 91.6, 84.2, 82.1, 81.0, 75.4%, respectively. Among all age bands, the PRP is lowest among children less than 12-month-age, followed by people over 15 years old. CONCLUSION: Measles antibody level among healthy population has been declined since 2012, supplemented measles vaccination activity may be necessary to eliminate measles in China.
BACKGROUND: To eliminate measles, the coverage of more than 90% vaccine is required in China. Nonetheless, the measles incidence still reached to 3.88 per 100,000 in 2014, which is far more than the target of 1 per 1,000,000. Moreover, there is little national surveillance to measles antibody level indicating herd immunity status in China. METHODS: We detected the level of antibody to measles using commercially available indirect enzyme-linked immunosorbent IgG assays, and calculated the protection rate of population (PRP) to measlesvirus infection among health peoples in China. RESULTS: During the years 2009-2015, among the Chinese population aged 0-56, PRP was 94.7, 91.6, 91.6, 84.2, 82.1, 81.0, 75.4%, respectively. Among all age bands, the PRP is lowest among children less than 12-month-age, followed by people over 15 years old. CONCLUSION:Measles antibody level among healthy population has been declined since 2012, supplemented measles vaccination activity may be necessary to eliminate measles in China.
Entities:
Keywords:
Antibody level; Herd immunity; Measles elimination; Measles virus; Protection rate of population
Authors: Emmaculate J Lebo; Deanna M Kruszon-Moran; Mona Marin; William J Bellini; Scott Schmid; Stephanie R Bialek; Gregory S Wallace; Huong Q McLean Journal: Open Forum Infect Dis Date: 2015-02-20 Impact factor: 3.835
Authors: Robert T Perry; Marta Gacic-Dobo; Alya Dabbagh; Mick N Mulders; Peter M Strebel; Jean-Marie Okwo-Bele; Paul A Rota; James L Goodson Journal: MMWR Morb Mortal Wkly Rep Date: 2014-11-14 Impact factor: 17.586