Literature DB >> 30040550

Uterus Transplantation: The Ethics of Using Deceased Versus Living Donors.

Bethany Bruno1, Kavita Shah Arora2.   

Abstract

Research teams have made considerable progress in treating absolute uterine factor infertility through uterus transplantation, though studies have differed on the choice of either deceased or living donors. While researchers continue to analyze the medical feasibility of both approaches, little attention has been paid to the ethics of using deceased versus living donors as well as the protections that must be in place for each. Both types of uterus donation also pose unique regulatory challenges, including how to allocate donated organs; whether the donor / donor's family has any rights to the uterus and resulting child; how to manage contact between the donor / donor's family, recipient, and resulting child; and how to track outcomes moving forward.

Entities:  

Keywords:  informed consent; organ transplantation; rationing/resource allocation; regulatory issues; reproductive technologies

Mesh:

Year:  2018        PMID: 30040550      PMCID: PMC6296249          DOI: 10.1080/15265161.2018.1478018

Source DB:  PubMed          Journal:  Am J Bioeth        ISSN: 1526-5161            Impact factor:   11.229


  50 in total

1.  Justification of living-organ donation requires benefit for the donor that balances the risk: Commentary on Ross et al.

Authors:  Aaron Spital
Journal:  Transplantation       Date:  2002-08-15       Impact factor: 4.939

2.  Donor benefit is the key to justified living organ donation.

Authors:  Aaron Spital
Journal:  Camb Q Healthc Ethics       Date:  2004       Impact factor: 1.284

3.  Ethical guidelines for the evaluation of living organ donors.

Authors:  Linda Wright; Karen Faith; Robert Richardson; David Grant
Journal:  Can J Surg       Date:  2004-12       Impact factor: 2.089

4.  Ethical considerations in the era of the uterine transplant: an update of the Montreal Criteria for the Ethical Feasibility of Uterine Transplantation.

Authors:  Ariel Lefkowitz; Marcel Edwards; Jacques Balayla
Journal:  Fertil Steril       Date:  2013-06-12       Impact factor: 7.329

5.  The dead-donor rule and the future of organ donation.

Authors:  Robert D Truog; Franklin G Miller; Scott D Halpern
Journal:  N Engl J Med       Date:  2013-10-03       Impact factor: 91.245

Review 6.  The future of human uterus transplantation.

Authors:  Liza Johannesson; Pernilla Dahm-Kähler; Saskia Eklind; Mats Brännström
Journal:  Womens Health (Lond)       Date:  2014-07

7.  Emotional and Financial Experiences of Kidney Donors over the Past 50 Years: The RELIVE Study.

Authors:  Cheryl L Jacobs; Cynthia R Gross; Emily E Messersmith; Barry A Hong; Brenda W Gillespie; Peg Hill-Callahan; Sandra J Taler; Sheila G Jowsey; Tim J Beebe; Arthur J Matas; Jonah Odim; Hassan N Ibrahim
Journal:  Clin J Am Soc Nephrol       Date:  2015-10-13       Impact factor: 8.237

8.  Inhibin B and ovarian function after total abdominal hysterectomy in women of reproductive age.

Authors:  E Nahás; A Pontes; P Traiman; J NahásNeto; I Dalben; L De Luca
Journal:  Gynecol Endocrinol       Date:  2003-04       Impact factor: 2.260

9.  Endometrial exosomes/microvesicles in the uterine microenvironment: a new paradigm for embryo-endometrial cross talk at implantation.

Authors:  York Hunt Ng; Sophie Rome; Audrey Jalabert; Alexis Forterre; Harmeet Singh; Cassandra L Hincks; Lois A Salamonsen
Journal:  PLoS One       Date:  2013-03-13       Impact factor: 3.240

10.  Should Deceased Donation be Morally Preferred in Uterine Transplantation Trials?

Authors:  Nicola Williams
Journal:  Bioethics       Date:  2016-02-01       Impact factor: 1.898

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  10 in total

1.  Uterine Transplantation Using Living Donation: A Cross-sectional Study Assessing Perceptions, Acceptability, and Suitability.

Authors:  Benjamin P Jones; Abirami Rajamanoharan; Nicola J Williams; Saaliha Vali; Srdjan Saso; Ifigenia Mantrali; Maria Jalmbrant; Meen-Yau Thum; Cesar Diaz-Garcia; Sadaf Ghaem-Maghami; Stephen Wilkinson; Isabel Quiroga; Peter Friend; Joseph Yazbek; J Richard Smith
Journal:  Transplant Direct       Date:  2021-02-18

Review 2.  Uterus transplantation: state of the art in 2021.

Authors:  Elliott G Richards; Ruth M Farrell; Stephanie Ricci; Uma Perni; Cristiano Quintini; Andreas Tzakis; Tommaso Falcone
Journal:  J Assist Reprod Genet       Date:  2021-05-31       Impact factor: 3.357

3.  The Ethics of the Societal Entrenchment-approach and the case of live uterus transplantation-IVF.

Authors:  Lisa Guntram; Kristin Zeiler
Journal:  Med Health Care Philos       Date:  2019-12

4.  Feasibility study for performing uterus transplantation in the Netherlands.

Authors:  H E Peters; L J M Juffermans; C B Lambalk; J J M L Dekker; T Fernhout; F A Groenman; C J M de Groot; A W J Hoksbergen; J A F Huirne; R A de Leeuw; N M van Mello; J H Nederhoed; R Schats; M O Verhoeven; W J K Hehenkamp
Journal:  Hum Reprod Open       Date:  2020-02-28

5.  Human Uterus Transplantation from Living and Deceased Donors: The Interim Results of the First 10 Cases of the Czech Trial.

Authors:  Jiri Fronek; Jakub Kristek; Jaroslav Chlupac; Libor Janousek; Michael Olausson
Journal:  J Clin Med       Date:  2021-02-04       Impact factor: 4.241

6.  The reproductive potential of uterus transplantation: future prospects.

Authors:  Giuseppe Gullo; Andrea Etrusco; Manuela Fabio; Gaspare Cucinella; Claudio Rossi; Valentina Billone
Journal:  Acta Biomed       Date:  2022-05-11

Review 7.  Options for acquiring motherhood in absolute uterine factor infertility; adoption, surrogacy and uterine transplantation.

Authors:  Benjamin P Jones; Niccole Ranaei-Zamani; Saaliha Vali; Nicola Williams; Srdjan Saso; Meen-Yau Thum; Maya Al-Memar; Nuala Dixon; Gillian Rose; Giuliano Testa; Liza Johannesson; Joseph Yazbek; Stephen Wilkinson; J Richard Smith
Journal:  Obstet Gynaecol       Date:  2021-03-19

Review 8.  Ethical and policy issues raised by uterus transplants.

Authors:  Laura O'Donovan; Nicola Jane Williams; Stephen Wilkinson
Journal:  Br Med Bull       Date:  2019-09-19       Impact factor: 4.291

Review 9.  Ethical Implications of Donor Type for Uterus Transplantation: Why We Should Remain Wary of Using Living Donors.

Authors:  Bethany Bruno; Kavita Shah Arora
Journal:  Yale J Biol Med       Date:  2020-09-30

10.  May I have your uterus? The contribution of considering complexities preceding live uterus transplantation.

Authors:  Lisa Guntram
Journal:  Med Humanit       Date:  2021-02-24
  10 in total

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