| Literature DB >> 3003932 |
J Hilkens, H T Cuypers, G Selten, V Kroezen, J Hilgers, A Berns.
Abstract
Pim-1 is a putative oncogene activated in T-cell lymphomas induced by Moloney and AKR mink cell focus forming (MCF) viruses. We have determined the chromosomal localization of the Pim-1 gene in mice by Southern blot analysis of DNAs obtained from a panel of mouse-Chinese hamster somatic cell hybrids. The Pim-1 gene was localized on chromosome 17, a chromosome frequently aberrant in T-cell lymphomas. Two chromosomal regions, containing sequences homologous to regions within the Pim-1 locus, were localized on chromosome 6 and 16.Entities:
Mesh:
Substances:
Year: 1986 PMID: 3003932 DOI: 10.1007/bf01560730
Source DB: PubMed Journal: Somat Cell Mol Genet ISSN: 0740-7750