Literature DB >> 30034154

Effect of Low-Dose Aspirin on Bleeding Following Exodontia: A Prospective Clinical Study.

Rohan Gupta1,2,3, Arun Dugal1, Vikrant Dilip Sane1, Shashank Hiwarkar1, Saurabh Khandelwal1, Apoorva Iyengar1.   

Abstract

PURPOSE: This research aims to study the effects of low-dose aspirin on bleeding after exodontia and to compare statistically and analyze perioperative blood loss during exodontia in patients on aspirin therapy and healthy patients and also to discuss the various measures if required necessary for controlling postoperative bleeding in simple and uncomplicated exodontia.
MATERIALS AND METHODS: The study included 100 patients, ranging in age from 30 to 60 years. The patients were divided into two groups, a test group consisting of 50 patients who were on a daily dose of 75-150 mg of aspirin and a control group consisting of 50 patients not on any antiplatelet therapy. All extraction procedures were performed on outpatient basis. Patients were operated under local anesthesia. Post-extraction sockets were checked for bleeding immediately (30 min) and followed up at 24, 48, and 72 h, and 1 week, after the procedure.
RESULTS: Amount of intraoperative blood loss was similar in both test and control groups, and there was no excessive postoperative bleeding in any case. Out of 100 patients, only three patients of test group and two patients of control group required level II hemostatic measures and two patients of test group needed level III measures.
CONCLUSION: We could reach a conclusion and recommend that patients on long-term low-dose aspirin (75-150 mg) need not to discontinue their aspirin dose prior to routine exodontia and can be carried out safely with enhanced local hemostatic measures, if required.

Entities:  

Keywords:  Acetylsalicylic acid; Antiplatelet therapy; Coronary artery disease; Local hemostatic agents

Year:  2017        PMID: 30034154      PMCID: PMC6028348          DOI: 10.1007/s12663-017-1034-7

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  25 in total

1.  Aspirin-induced oral bleeding: correction with platelet transfusion. A reminder.

Authors:  S R Lemkin; J E Billesdon; J S Davee; D L Leake; H E Kattlove
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1974-04

2.  Does low-dose aspirin therapy complicate oral surgical procedures?

Authors:  L Ardekian; R Gaspar; M Peled; B Brener; D Laufer
Journal:  J Am Dent Assoc       Date:  2000-03       Impact factor: 3.634

3.  Dental extraction for patients on oral anticoagulant therapy.

Authors:  U Martinowitz; A L Mazar; S Taicher; D Varon; S N Gitel; B Ramot; M Rakocz
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1990-09

4.  Views of cardiac-valve prosthesis patients and their dentists on anticoagulation therapy.

Authors:  S Lippert; E Gutschik
Journal:  Scand J Dent Res       Date:  1994-06

Review 5.  Aspirin to prevent heart attack and stroke: what's the right dose?

Authors:  James E Dalen
Journal:  Am J Med       Date:  2006-03       Impact factor: 4.965

6.  Exodontia and antiplatelet therapy.

Authors:  Balasubramanian Krishnan; Nithin A Shenoy; Mohan Alexander
Journal:  J Oral Maxillofac Surg       Date:  2008-10       Impact factor: 1.895

Review 7.  Aspirin and bleeding in dentistry: an update and recommendations.

Authors:  Michael T Brennan; Richard L Wynn; Craig S Miller
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2007-07-06

8.  Dental extractions in patients on antiplatelet therapy. A study conducted by the Oral Health Department of the Navarre Health Service (Spain).

Authors:  Francisco Cardona-Tortajada; Esther Sainz-Gómez; Jorge Figuerido-Garmendia; Ana Lirón de Robles-Adsuar; Antonio Morte-Casabó; Fernando Giner-Muñoz; Joaquín Artázcoz-Osés; Javier Vidán-Lizari
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2009-11-01

9.  The effect of platelet-altering medications on bleeding from minor oral surgery procedures.

Authors:  Corbin G Partridge; John H Campbell; Fernando Alvarado
Journal:  J Oral Maxillofac Surg       Date:  2008-01       Impact factor: 1.895

10.  Hemostatic management of tooth extractions in patients on oral antithrombotic therapy.

Authors:  Yoshinari Morimoto; Hitoshi Niwa; Kazuo Minematsu
Journal:  J Oral Maxillofac Surg       Date:  2008-01       Impact factor: 1.895

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  1 in total

1.  Bleeding Complications in Anticoagulated and/or Antiplatelet-Treated Patients at the Dental Office: A Retrospective Study.

Authors:  Esther Martínez-Moreno; Federico Martínez-López; Francisco Javier Rodríguez-Lozano; Ricardo Elías Oñate-Sánchez
Journal:  Int J Environ Res Public Health       Date:  2021-02-08       Impact factor: 3.390

  1 in total

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