PURPOSE: This study was performed to assess the extent of bleeding from minor oral surgical procedures in patients taking platelet-altering medications. They were compared with patients who were not taking platelet-altering medicines to assess differences in extent of blood loss. MATERIALS AND METHODS: A prospective observational study design was used to quantitatively assess the amount and severity of bleeding encountered with dentoalveolar surgery in 2 groups. The experimental group consisted of people taking therapeutic doses of platelet-altering medications, and the control group was composed of patients who had not taken a platelet-altering medication for at least 10 days prior to surgery. Surgical blood loss was measured, and the groups were compared for statistically significant differences in blood loss. RESULTS: There was no difference in blood loss detected between the experimental or control groups. No bleeding complications were encountered. CONCLUSION: Our data suggest that patients on aspirin and NSAIDs can safely undergo routine minor outpatient oral surgical procedures without modification of their platelet-altering medication.
PURPOSE: This study was performed to assess the extent of bleeding from minor oral surgical procedures in patients taking platelet-altering medications. They were compared with patients who were not taking platelet-altering medicines to assess differences in extent of blood loss. MATERIALS AND METHODS: A prospective observational study design was used to quantitatively assess the amount and severity of bleeding encountered with dentoalveolar surgery in 2 groups. The experimental group consisted of people taking therapeutic doses of platelet-altering medications, and the control group was composed of patients who had not taken a platelet-altering medication for at least 10 days prior to surgery. Surgical blood loss was measured, and the groups were compared for statistically significant differences in blood loss. RESULTS: There was no difference in blood loss detected between the experimental or control groups. No bleeding complications were encountered. CONCLUSION: Our data suggest that patients on aspirin and NSAIDs can safely undergo routine minor outpatient oral surgical procedures without modification of their platelet-altering medication.
Authors: Alexander Gröbe; Meike Fraederich; Ralf Smeets; Max Heiland; Lan Kluwe; Jürgen Zeuch; Martina Haase; Johannes Wikner; Henning Hanken; Jan Semmusch; Ahmed Al-Dam; Wolfgang Eichhorn Journal: Biomed Res Int Date: 2015-01-06 Impact factor: 3.411