Marie Herr1,2,3, Bernard Jeune4, Stefan Fors5, Karen Andersen-Ranberg4, Joël Ankri1,2,3, Yasu Arai6, Sarah Cubaynes7, Brigitte Santos-Eggimann8, Dina Zekry9, Marti Parker5, Yasuhiko Saito10, François Herrmann9, Jean-Marie Robine7. 1. INSERM, U1168, VIMA: Aging and Chronic Diseases, Epidemiological and Public Health Approaches, Villejuif, France. 2. Université de Versailles St-Quentin-en-Yvelines, UMR-S 1168, Montigny le Bretonneux, France. 3. Département Hospitalier d'Epidémiologie et Santé Publique, Hôpitaux Universitaires Paris Ile-de-France Ouest, Assistance Publique-Hôpitaux de Paris, Paris, France. 4. Epidemiology and Biostatistics, Institute of Public Health, and Danish Aging Research Centre, University of Southern Denmark, Odense, Denmark. 5. Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden. 6. Center for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan. 7. MMDN, Université de Montpellier, EPHE, INSERM, U1198, PSL Research University, Montpellier, France. 8. Lausanne University Hospital, Institute of Social and Preventive Medicine, Lausanne, Switzerland. 9. Division of Geriatrics, Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals and University of Geneva, Geneva, Switzerland. 10. University Research Center, Nihon University, Tokyo, Japan.
Abstract
BACKGROUND: The global number of centenarians is still strongly growing and information about the health and healthcare needs of this segment of the population is needed. This study aimed to estimate the prevalence of frailty among centenarians included in a multinational study and to investigate associated factors. METHODS: The 5-COOP study is a cross-sectional survey including 1,253 centenarians in 5 countries (Japan, France, Switzerland, Denmark, and Sweden). Data were collected using a standardized questionnaire during a face-to-face interview (73.3%), telephone interview (14.5%), or by postal questionnaire (12.2%). The 5 dimensions of the frailty phenotype (weight loss, fatigue, weakness, slow walking speed, and low level of physical activity) were assessed by using self-reported data. Factors associated with frailty criteria were investigated by using multivariate regression models. RESULTS: Almost 95% of the participants had at least 1 frailty criterion. The overall prevalence of frailty (3 criteria or more) was 64.7% (from 51.5% in Sweden to 77.6% in Switzerland), and 32.2% of the participants had 4 or 5 criteria. The most frequent criteria were weakness (84.2%), slow walking speed (77.6%), and low level of physical activity (72.5%), followed by fatigue (43.8%) and weight loss (23.8%). Factors associated with frailty included data collection modes, country of residence, gender, living in institution, depression, dementia, disability, falls, and sensory impairments. CONCLUSIONS: This study shows that reaching 100 years of age rarely goes without frailty and sheds light on factors associated with frailty at a very old age.
BACKGROUND: The global number of centenarians is still strongly growing and information about the health and healthcare needs of this segment of the population is needed. This study aimed to estimate the prevalence of frailty among centenarians included in a multinational study and to investigate associated factors. METHODS: The 5-COOP study is a cross-sectional survey including 1,253 centenarians in 5 countries (Japan, France, Switzerland, Denmark, and Sweden). Data were collected using a standardized questionnaire during a face-to-face interview (73.3%), telephone interview (14.5%), or by postal questionnaire (12.2%). The 5 dimensions of the frailty phenotype (weight loss, fatigue, weakness, slow walking speed, and low level of physical activity) were assessed by using self-reported data. Factors associated with frailty criteria were investigated by using multivariate regression models. RESULTS: Almost 95% of the participants had at least 1 frailty criterion. The overall prevalence of frailty (3 criteria or more) was 64.7% (from 51.5% in Sweden to 77.6% in Switzerland), and 32.2% of the participants had 4 or 5 criteria. The most frequent criteria were weakness (84.2%), slow walking speed (77.6%), and low level of physical activity (72.5%), followed by fatigue (43.8%) and weight loss (23.8%). Factors associated with frailty included data collection modes, country of residence, gender, living in institution, depression, dementia, disability, falls, and sensory impairments. CONCLUSIONS: This study shows that reaching 100 years of age rarely goes without frailty and sheds light on factors associated with frailty at a very old age.
Authors: Monica C Tembo; Kara L Holloway-Kew; Mohammadreza Mohebbi; Sophia X Sui; Sarah M Hosking; Sharon L Brennan-Olsen; Lana J Williams; Mark A Kotowicz; Julie A Pasco Journal: BMC Geriatr Date: 2020-06-05 Impact factor: 3.921
Authors: Kadjo Yves Cedric Adja; Jacopo Lenzi; Duygu Sezgin; Rónán O'Caoimh; Mara Morini; Gianfranco Damiani; Alessandra Buja; Maria Pia Fantini Journal: Front Public Health Date: 2020-11-12
Authors: Dayane Capra de Oliveira; Roberta de Oliveira Máximo; Paula Camila Ramírez; Aline Fernanda de Souza; Mariane Marques Luiz; Maicon Luis Bicigo Delinocente; Marcos Hortes Nisihara Chagas; Andrew Steptoe; Cesar de Oliveira; Tiago da Silva Alexandre Journal: J Cachexia Sarcopenia Muscle Date: 2021-09-29 Impact factor: 12.910
Authors: Julien Dupraz; Karen Andersen-Ranberg; Stefan Fors; Marie Herr; Francois R Herrmann; Tomoko Wakui; Bernard Jeune; Jean-Marie Robine; Yasuhiko Saito; Brigitte Santos-Eggimann Journal: BMJ Open Date: 2020-03-24 Impact factor: 2.692