Guido Giusti1, Silvia Proietti2, Moises E Rodríguez-Socarrás2, Brian H Eisner3, Giuseppe Saitta4, Guglielmo Mantica2, Luca Villa5, Andrea Salonia5, Francesco Montorsi5, Franco Gaboardi2. 1. Department of Urology, IRCCS San Raffaele Hospital, Ville Turro Division, Milan, Italy. Electronic address: drguidogiusti@gmail.com. 2. Department of Urology, IRCCS San Raffaele Hospital, Ville Turro Division, Milan, Italy. 3. Department of Urology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA. 4. Department of Urology, IRCCS San Raffaele Hospital, Ville Turro Division, Milan, Italy; Division of Experimental Oncology/Unit of Urology, URI, IRCCS San Raffaele Hospital, Milan, Italy. 5. Division of Experimental Oncology/Unit of Urology, URI, IRCCS San Raffaele Hospital, Milan, Italy.
Abstract
BACKGROUND: The incidence of bilateral and multiple renal stones is not negligible. To date, some sparse data on simultaneous bilateral stone surgery are available in literature showing good outcomes in terms of both effectiveness and safety. OBJECTIVE: To describe our series of patients with bilateral renal stones who underwent simultaneous bilateral endoscopic surgery (SBES), reporting its effectiveness and safety. DESIGN, SETTING, AND PARTICIPANTS: A prospective analysis of 27 consecutive patients who underwent simultaneous flexible ureteroscopy (fURS) in one side and percutaneous nephrolithotomy (PCNL) in the other side for bilateral renal stones was performed. SURGICAL PROCEDURE: SBES, performing fURS in one side and PCNL in the other side contemporaneously. MEASUREMENTS: Clinical data were collected in a dedicated database. Intra- and postoperative outcomes were assessed. Comparisons among pre- and postoperative serum creatinine levels and estimated glomerular filtration rate values during the study period were performed using the Kruskal-Wallis test with the Dunn multiple comparison test. RESULTS AND LIMITATIONS: All the procedures were carried out until the end in both sides without encountering any complications intraoperatively. The mean stone size was 27.1±8.1 and 11.1±3.6mm for the PCNL and fURS side respectively. The mean operative time was 79.4±25.2min. There were no differences in patients' creatinine and eGFR when comparing at baseline with 1-mo after SBES. No postoperative major complications were experienced (Clavien-Dindo grade I 3.7%; II 11.1%). Stone-free rate was 74% at 1-mo follow-up. The main limitation of the study is the small size of the group analyzed. CONCLUSIONS: SBES is safe and effective, with minimal morbidity. SBES has the potential advantages of shorter operative time, reduced anesthesia, and reduced hospital time, which can benefit patients, surgeons, and health care systems. PATIENT SUMMARY: Simultaneous bilateral endoscopic surgery is an effective treatment with low complication rates for bilateral urolithiasis. This innovative and complicated procedure should be performed in high-volume centers by experienced surgeons.
BACKGROUND: The incidence of bilateral and multiple renal stones is not negligible. To date, some sparse data on simultaneous bilateral stone surgery are available in literature showing good outcomes in terms of both effectiveness and safety. OBJECTIVE: To describe our series of patients with bilateral renal stones who underwent simultaneous bilateral endoscopic surgery (SBES), reporting its effectiveness and safety. DESIGN, SETTING, AND PARTICIPANTS: A prospective analysis of 27 consecutive patients who underwent simultaneous flexible ureteroscopy (fURS) in one side and percutaneous nephrolithotomy (PCNL) in the other side for bilateral renal stones was performed. SURGICAL PROCEDURE: SBES, performing fURS in one side and PCNL in the other side contemporaneously. MEASUREMENTS: Clinical data were collected in a dedicated database. Intra- and postoperative outcomes were assessed. Comparisons among pre- and postoperative serum creatinine levels and estimated glomerular filtration rate values during the study period were performed using the Kruskal-Wallis test with the Dunn multiple comparison test. RESULTS AND LIMITATIONS: All the procedures were carried out until the end in both sides without encountering any complications intraoperatively. The mean stone size was 27.1±8.1 and 11.1±3.6mm for the PCNL and fURS side respectively. The mean operative time was 79.4±25.2min. There were no differences in patients' creatinine and eGFR when comparing at baseline with 1-mo after SBES. No postoperative major complications were experienced (Clavien-Dindo grade I 3.7%; II 11.1%). Stone-free rate was 74% at 1-mo follow-up. The main limitation of the study is the small size of the group analyzed. CONCLUSIONS: SBES is safe and effective, with minimal morbidity. SBES has the potential advantages of shorter operative time, reduced anesthesia, and reduced hospital time, which can benefit patients, surgeons, and health care systems. PATIENT SUMMARY: Simultaneous bilateral endoscopic surgery is an effective treatment with low complication rates for bilateral urolithiasis. This innovative and complicated procedure should be performed in high-volume centers by experienced surgeons.
Authors: Silvia Proietti; Moises Elias Rodríguez-Socarrás; Brian Eisner; Vincent De Coninck; Mario Sofer; Giuseppe Saitta; Maria Rodriguez-Monsalve; Carlo D'Orta; Piera Bellinzoni; Franco Gaboardi; Guido Giusti Journal: Transl Androl Urol Date: 2019-09
Authors: Oriol Angerri; Olga Mayordomo; Andres Koey Kanashiro; Felix Millan-Rodriguez; Francisco Maria Sanchez-Martin; Sung-Yo Cho; Eran Schreter; Mario Sofer; Saeed Bin-Hamri; Ahmed Alasker; Yiloren Tanidir; Tarik Emre Sener; Panagiotis Kalidonis; Joan Palou-Redorta; Esteban Emiliani Journal: Cent European J Urol Date: 2019-05-30