Literature DB >> 30010924

Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come?

Chi Keung Lam1,2, Joseph C Wu1,2,3.   

Abstract

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Year:  2018        PMID： 30010924      PMCID： PMC6234848          DOI： 10.1093/eurheartj/ehy388

Source DB:  PubMed          Journal:  Eur Heart J        ISSN： 0195-668X            Impact factor:   29.983


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  16 in total

1.  Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system.

Authors:  Antje D Ebert; Kazuki Kodo; Ping Liang; Haodi Wu; Bruno C Huber; Johannes Riegler; Jared Churko; Jaecheol Lee; Patricia de Almeida; Feng Lan; Sebastian Diecke; Paul W Burridge; Joseph D Gold; Daria Mochly-Rosen; Joseph C Wu
Journal:  Sci Transl Med       Date:  2014-09-24       Impact factor: 17.956

Review 2.  Hypertrophic Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.

Authors:  Ali J Marian; Eugene Braunwald
Journal:  Circ Res       Date:  2017-09-15       Impact factor: 17.367

3.  Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.

Authors:  Paul W Burridge; Yong Fuga Li; Elena Matsa; Haodi Wu; Sang-Ging Ong; Arun Sharma; Alexandra Holmström; Alex C Chang; Michael J Coronado; Antje D Ebert; Joshua W Knowles; Melinda L Telli; Ronald M Witteles; Helen M Blau; Daniel Bernstein; Russ B Altman; Joseph C Wu
Journal:  Nat Med       Date:  2016-04-18       Impact factor: 53.440

Review 4.  Hurdles to clinical translation of human induced pluripotent stem cells.

Authors:  Evgenios Neofytou; Connor Galen O'Brien; Larry A Couture; Joseph C Wu
Journal:  J Clin Invest       Date:  2015-07-01       Impact factor: 14.808

5.  Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.

Authors:  Michiko Mandai; Akira Watanabe; Yasuo Kurimoto; Yasuhiko Hirami; Chikako Morinaga; Takashi Daimon; Masashi Fujihara; Hiroshi Akimaru; Noriko Sakai; Yumiko Shibata; Motoki Terada; Yui Nomiya; Shigeki Tanishima; Masahiro Nakamura; Hiroyuki Kamao; Sunao Sugita; Akishi Onishi; Tomoko Ito; Kanako Fujita; Shin Kawamata; Masahiro J Go; Chikara Shinohara; Ken-Ichiro Hata; Masanori Sawada; Midori Yamamoto; Sachiko Ohta; Yasuo Ohara; Kenichi Yoshida; Junko Kuwahara; Yuko Kitano; Naoki Amano; Masafumi Umekage; Fumiyo Kitaoka; Azusa Tanaka; Chihiro Okada; Naoko Takasu; Seishi Ogawa; Shinya Yamanaka; Masayo Takahashi
Journal:  N Engl J Med       Date:  2017-03-16       Impact factor: 91.245

6.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

7.  Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

Authors:  Ning Sun; Masayuki Yazawa; Jianwei Liu; Leng Han; Veronica Sanchez-Freire; Oscar J Abilez; Enrique G Navarrete; Shijun Hu; Li Wang; Andrew Lee; Aleksandra Pavlovic; Shin Lin; Rui Chen; Roger J Hajjar; Michael P Snyder; Ricardo E Dolmetsch; Manish J Butte; Euan A Ashley; Michael T Longaker; Robert C Robbins; Joseph C Wu
Journal:  Sci Transl Med       Date:  2012-04-18       Impact factor: 17.956

8.  Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy.

Authors:  G Hasenfuss; C Holubarsch; H P Hermann; K Astheimer; B Pieske; H Just
Journal:  Eur Heart J       Date:  1994-02       Impact factor: 29.983

9.  Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond.

Authors:  Chun Liu; Angelos Oikonomopoulos; Nazish Sayed; Joseph C Wu
Journal:  Development       Date:  2018-03-08       Impact factor: 6.868

10.  Advanced maturation of human cardiac tissue grown from pluripotent stem cells.

Authors:  Kacey Ronaldson-Bouchard; Stephen P Ma; Keith Yeager; Timothy Chen; LouJin Song; Dario Sirabella; Kumi Morikawa; Diogo Teles; Masayuki Yazawa; Gordana Vunjak-Novakovic
Journal:  Nature       Date:  2018-04-04       Impact factor: 49.962
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  4 in total

1.  Disrupted mechanobiology links the molecular and cellular phenotypes in familial dilated cardiomyopathy.

Authors:  Sarah R Clippinger; Paige E Cloonan; Lina Greenberg; Melanie Ernst; W Tom Stump; Michael J Greenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2019-08-19       Impact factor: 11.205

Review 2.  Human Pluripotent Stem Cell-Derived Cardiac Cells: Application in Disease Modeling, Cell Therapy, and Drug Discovery.

Authors:  Juan Huang; Qi Feng; Li Wang; Bingying Zhou
Journal:  Front Cell Dev Biol       Date:  2021-04-01

3.  Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation.

Authors:  Sarah R Clippinger; Paige E Cloonan; Wei Wang; Lina Greenberg; W Tom Stump; Paweorn Angsutararux; Jeanne M Nerbonne; Michael J Greenberg
Journal:  J Gen Physiol       Date:  2021-05-03       Impact factor: 4.086

Review 4.  The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases.

Authors:  Marc Pourrier; David Fedida
Journal:  Int J Mol Sci       Date:  2020-01-19       Impact factor: 5.923
  4 in total

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