Literature DB >> 30008982

EMDB Web Resources.

Sanja Abbott1, Andrii Iudin1, Paul K Korir1, Sriram Somasundharam1, Ardan Patwardhan1.   

Abstract

The Electron Microscopy Data Bank (EMDB; http://emdb-empiar.org) is a global openly-accessible archive of biomolecular and cellular 3D reconstructions derived from electron microscopy (EM) data. EMBL-EBI develops web-based resources to facilitate the reuse of EMDB data. Here we provide protocols for how these resources can be used for searching EMDB, visualising EMDB structures, statistically analysing EMDB content and checking the validity of EMDB structures. Protocols for searching include quick link categories from the main page, links to latest entries released during the weekly cycle, filtered browsing of the entire archive and a form-based search. For visualisation, the 'Volume Slicer' enables slices of EMDB entries to be visualised interactively and in three orthogonal directions. The EMstats web service (https://emdb-empiar.org/emstats) provides up-to-date interactive statistical charts analysing EMDB. All EMDB entries have 'visual analysis' pages that provide basic validation information for the entry.

Entities:  

Keywords:  Cryo-electron microscopy; EMDB; electron tomography; search; single particle image processing; structure; validation

Mesh:

Year:  2018        PMID: 30008982      PMCID: PMC6040833          DOI: 10.1002/cpbi.48

Source DB:  PubMed          Journal:  Curr Protoc Bioinformatics        ISSN: 1934-3396


  6 in total

1.  New electron microscopy database and deposition system.

Authors:  Mohamed Tagari; Richard Newman; Monica Chagoyen; Jose Maria Carazo; Kim Henrick
Journal:  Trends Biochem Sci       Date:  2002-11       Impact factor: 13.807

2.  Web-based visualisation and analysis of 3D electron-microscopy data from EMDB and PDB.

Authors:  Ingvar Lagerstedt; William J Moore; Ardan Patwardhan; Eduardo Sanz-García; Christoph Best; Jason R Swedlow; Gerard J Kleywegt
Journal:  J Struct Biol       Date:  2013-10-07       Impact factor: 2.867

3.  Trends in the Electron Microscopy Data Bank (EMDB).

Authors:  Ardan Patwardhan
Journal:  Acta Crystallogr D Struct Biol       Date:  2017-04-20       Impact factor: 7.652

Review 4.  Databases and Archiving for CryoEM.

Authors:  A Patwardhan; C L Lawson
Journal:  Methods Enzymol       Date:  2016-06-16       Impact factor: 1.600

5.  PDBe: Protein Data Bank in Europe.

Authors:  Aleksandras Gutmanas; Younes Alhroub; Gary M Battle; John M Berrisford; Estelle Bochet; Matthew J Conroy; Jose M Dana; Manuel A Fernandez Montecelo; Glen van Ginkel; Swanand P Gore; Pauline Haslam; Rowan Hatherley; Pieter M S Hendrickx; Miriam Hirshberg; Ingvar Lagerstedt; Saqib Mir; Abhik Mukhopadhyay; Thomas J Oldfield; Ardan Patwardhan; Luana Rinaldi; Gaurav Sahni; Eduardo Sanz-García; Sanchayita Sen; Robert A Slowley; Sameer Velankar; Michael E Wainwright; Gerard J Kleywegt
Journal:  Nucleic Acids Res       Date:  2013-11-27       Impact factor: 16.971

6.  Web-based volume slicer for 3D electron-microscopy data from EMDB.

Authors:  José Salavert-Torres; Andrii Iudin; Ingvar Lagerstedt; Eduardo Sanz-García; Gerard J Kleywegt; Ardan Patwardhan
Journal:  J Struct Biol       Date:  2016-02-10       Impact factor: 2.867

  6 in total
  10 in total

1.  The Protein Data Bank Archive.

Authors:  Sameer Velankar; Stephen K Burley; Genji Kurisu; Jeffrey C Hoch; John L Markley
Journal:  Methods Mol Biol       Date:  2021

2.  Simplified quality assessment for small-molecule ligands in the Protein Data Bank.

Authors:  Chenghua Shao; John D Westbrook; Changpeng Lu; Charmi Bhikadiya; Ezra Peisach; Jasmine Y Young; Jose M Duarte; Robert Lowe; Sijian Wang; Yana Rose; Zukang Feng; Stephen K Burley
Journal:  Structure       Date:  2022-01-12       Impact factor: 5.006

Review 3.  Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease.

Authors:  William Martin; Gloria Sheynkman; Felice C Lightstone; Ruth Nussinov; Feixiong Cheng
Journal:  Curr Opin Struct Biol       Date:  2021-10-07       Impact factor: 6.809

4.  Assessing PDB macromolecular crystal structure confidence at the individual amino acid residue level.

Authors:  Chenghua Shao; Sebastian Bittrich; Sijian Wang; Stephen K Burley
Journal:  Structure       Date:  2022-08-31       Impact factor: 5.871

Review 5.  Moving beyond static snapshots: Protein dynamics and the Protein Data Bank.

Authors:  Mitchell D Miller; George N Phillips
Journal:  J Biol Chem       Date:  2021-05-04       Impact factor: 5.157

6.  A collection of yeast cellular electron cryotomography data.

Authors:  Lu Gan; Cai Tong Ng; Chen Chen; Shujun Cai
Journal:  Gigascience       Date:  2019-06-01       Impact factor: 6.524

Review 7.  The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies.

Authors:  Vaishali P Waman; Neeladri Sen; Mihaly Varadi; Antoine Daina; Shoshana J Wodak; Vincent Zoete; Sameer Velankar; Christine Orengo
Journal:  Brief Bioinform       Date:  2021-03-22       Impact factor: 11.622

8.  Complex Portal 2022: new curation frontiers.

Authors:  Birgit H M Meldal; Livia Perfetto; Colin Combe; Tiago Lubiana; João Vitor Ferreira Cavalcante; Hema Bye-A-Jee; Andra Waagmeester; Noemi Del-Toro; Anjali Shrivastava; Elisabeth Barrera; Edith Wong; Bernhard Mlecnik; Gabriela Bindea; Kalpana Panneerselvam; Egon Willighagen; Juri Rappsilber; Pablo Porras; Henning Hermjakob; Sandra Orchard
Journal:  Nucleic Acids Res       Date:  2022-01-07       Impact factor: 16.971

9.  PDBe and PDBe-KB: Providing high-quality, up-to-date and integrated resources of macromolecular structures to support basic and applied research and education.

Authors:  Mihaly Varadi; Stephen Anyango; Sri Devan Appasamy; David Armstrong; Marcus Bage; John Berrisford; Preeti Choudhary; Damian Bertoni; Mandar Deshpande; Grisell Diaz Leines; Joseph Ellaway; Genevieve Evans; Romana Gaborova; Deepti Gupta; Aleksandras Gutmanas; Deborah Harrus; Gerard J Kleywegt; Weslley Morellato Bueno; Nurul Nadzirin; Sreenath Nair; Lukas Pravda; Marcelo Querino Lima Afonso; David Sehnal; Ahsan Tanweer; James Tolchard; Charlotte Abrams; Roisin Dunlop; Sameer Velankar
Journal:  Protein Sci       Date:  2022-10       Impact factor: 6.993

10.  UCSF ChimeraX: Structure visualization for researchers, educators, and developers.

Authors:  Eric F Pettersen; Thomas D Goddard; Conrad C Huang; Elaine C Meng; Gregory S Couch; Tristan I Croll; John H Morris; Thomas E Ferrin
Journal:  Protein Sci       Date:  2020-10-22       Impact factor: 6.993

  10 in total

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