PURPOSE: The purpose of this study was to analyze the clinical efficacy and complications of endoscopic submucosal dissection (ESD) and laparoscopic resection of stromal tumors, and to explore the clinical value and complications of stromal tumors treated with ESD. METHODS: 146 patients with gastric stromal tumors (GSTs) treated in our hospital from January 2012 to January 2016 were retrospectively analyzed. Patients were divided into the ESD group and the laparoscopic surgery group (LS). The operation time, postoperative recovery time of diet, postoperative exhaust time, etc were observed and analyzed. All the measurement indexes were described as mean ± standard deviation. The t-test of two independent samples was used for the hypothesis test. Chi-square test was used for comparison of the percent data between the two groups and p<0.05 indicated significant difference. RESULTS: The postoperative diet recovery time, postoperative exhaust time, hospital stay and hospitalization cost of the ESD group were better compared with the LS group (p<0.001). There was no significant difference in operative time between the ESD and LS group (p>0.05), while the operation time in ESD group was longer than in the LS group (p<0.05). The operation time of gastric body and antrum stromal tumors was shorter than in the ESD group group (p<0.05). There were no significant differences in tumor diameter, mitotic number and Flether classification between the groups (p>0.05). No significant difference in the incidence of postoperative bleeding, incision infection and recurrence rate was noticeable between the groups (p>0.05). CONCLUSIONS: Endoscopic treatment of GSTs is safe and feasible, and may be better than laparoscopic resection.
PURPOSE: The purpose of this study was to analyze the clinical efficacy and complications of endoscopic submucosal dissection (ESD) and laparoscopic resection of stromal tumors, and to explore the clinical value and complications of stromal tumors treated with ESD. METHODS: 146 patients with gastric stromal tumors (GSTs) treated in our hospital from January 2012 to January 2016 were retrospectively analyzed. Patients were divided into the ESD group and the laparoscopic surgery group (LS). The operation time, postoperative recovery time of diet, postoperative exhaust time, etc were observed and analyzed. All the measurement indexes were described as mean ± standard deviation. The t-test of two independent samples was used for the hypothesis test. Chi-square test was used for comparison of the percent data between the two groups and p<0.05 indicated significant difference. RESULTS: The postoperative diet recovery time, postoperative exhaust time, hospital stay and hospitalization cost of the ESD group were better compared with the LS group (p<0.001). There was no significant difference in operative time between the ESD and LS group (p>0.05), while the operation time in ESD group was longer than in the LS group (p<0.05). The operation time of gastric body and antrum stromal tumors was shorter than in the ESD group group (p<0.05). There were no significant differences in tumor diameter, mitotic number and Flether classification between the groups (p>0.05). No significant difference in the incidence of postoperative bleeding, incision infection and recurrence rate was noticeable between the groups (p>0.05). CONCLUSIONS: Endoscopic treatment of GSTs is safe and feasible, and may be better than laparoscopic resection.