Literature DB >> 3000136

A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo.

K A Jakobson, K L Kirk, J W Daly, B Jonzon, Y O Li, B B Fredholm.   

Abstract

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Year:  1985        PMID： 3000136      PMCID： PMC4351741          DOI： 10.1111/j.1748-1716.1985.tb07725.x

Source DB:  PubMed          Journal:  Acta Physiol Scand        ISSN： 0001-6772


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  3 in total

1.  Adenosine receptors.

Authors:  B B Fredholm
Journal:  Med Biol       Date:  1982-12

2.  Xanthine derivatives as adenosine receptor antagonists.

Authors:  B B Fredholm; C G Persson
Journal:  Eur J Pharmacol       Date:  1982-07-30       Impact factor: 4.432

3.  Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.

Authors:  K A Jacobson; K L Kirk; W L Padgett; J W Daly
Journal:  J Med Chem       Date:  1985-09       Impact factor: 7.446
  3 in total
  9 in total

1.  Influences of different adenosine receptor subtypes on catalepsy in mice.

Authors:  M R Zarrindast; M Modabber; M Sabetkasai
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

2.  Effects of adenosine agents on apomorphine-induced yawning in rats.

Authors:  M R Zarrindast; F Fatehi; M Mohagheghi-Badi
Journal:  Psychopharmacology (Berl)       Date:  1995-12       Impact factor: 4.530

3.  XAC, a functionalized congener of 1,3-dialkylxanthine, antagonizes A1 adenosine receptor-mediated inhibition of renin secretion in vitro.

Authors:  P C Churchill; K A Jacobson; M C Churchill
Journal:  Arch Int Pharmacodyn Ther       Date:  1987-12

4.  Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells.

Authors:  D Ukena; J W Daly; K L Kirk; K A Jacobson
Journal:  Life Sci       Date:  1986-03-03       Impact factor: 5.037

5.  A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.

Authors:  K A Jacobson; K L Kirk; W L Padgett; J W Daly
Journal:  Mol Pharmacol       Date:  1986-02       Impact factor: 4.436

6.  [3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors.

Authors:  K A Jacobson; D Ukena; K L Kirk; J W Daly
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

7.  Apparent affinity of some 8-phenyl-substituted xanthines at adenosine receptors in guinea-pig aorta and atria.

Authors:  M G Collis; K A Jacobson; D M Tomkins
Journal:  Br J Pharmacol       Date:  1987-09       Impact factor: 8.739

8.  Evidence that a novel 8-phenyl-substituted xanthine derivative is a cardioselective adenosine receptor antagonist in vivo.

Authors:  B B Fredholm; K A Jacobson; B Jonzon; K L Kirk; Y O Li; J W Daly
Journal:  J Cardiovasc Pharmacol       Date:  1987-04       Impact factor: 3.105

9.  Binary drugs: conjugates of purines and a peptide that bind to both adenosine and substance P receptors.

Authors:  K A Jacobson; A W Lipkowski; T W Moody; W Padgett; E Pijl; K L Kirk; J W Daly
Journal:  J Med Chem       Date:  1987-08       Impact factor: 7.446
  9 in total

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