Literature DB >> 29998253

The aerolysin nanopore: from peptidomic to genomic applications.

Yong Wang1, Li-Qun Gu2, Kai Tian2.   

Abstract

The aerolysin pore (ARP) is a newly emerging nanopore that has been extensively used for peptide and protein sensing. Recently, several groups have explored the application of ARP in detecting genetic and epigenetic markers. This brief review summarizes the current applications of ARP, progressing from peptidomic to genomic detection; the recently reported site-directed mutagenesis of ARP; and new genomic DNA sensing approaches, and their advantages and disadvantages. This review will also discuss the perspectives and future applications of ARP for nucleic acid sequencing and biomolecule sensing.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29998253      PMCID： PMC6157726          DOI： 10.1039/c8nr04255a

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


  53 in total

1.  Wild type, mutant protein unfolding and phase transition detected by single-nanopore recording.

Authors:  Céline Merstorf; Benjamin Cressiot; Manuela Pastoriza-Gallego; Abdelghani Oukhaled; Jean-Michel Betton; Loïc Auvray; Juan Pelta
Journal:  ACS Chem Biol       Date:  2012-02-02       Impact factor: 5.100

2.  Imaging alpha-hemolysin with molecular dynamics: ionic conductance, osmotic permeability, and the electrostatic potential map.

Authors:  Aleksij Aksimentiev; Klaus Schulten
Journal:  Biophys J       Date:  2005-03-11       Impact factor: 4.033

3.  Nanopore analysis of a small 86-residue protein.

Authors:  Radu Stefureac; Landon Waldner; Peter Howard; Jeremy S Lee
Journal:  Small       Date:  2008-01       Impact factor: 13.281

4.  Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient.

Authors:  Meni Wanunu; Will Morrison; Yitzhak Rabin; Alexander Y Grosberg; Amit Meller
Journal:  Nat Nanotechnol       Date:  2009-12-20       Impact factor: 39.213

5.  Single molecule detection of glycosaminoglycan hyaluronic acid oligosaccharides and depolymerization enzyme activity using a protein nanopore.

Authors:  Aziz Fennouri; Cédric Przybylski; Manuela Pastoriza-Gallego; Laurent Bacri; Loïc Auvray; Régis Daniel
Journal:  ACS Nano       Date:  2012-10-17       Impact factor: 15.881

6.  Driven Translocation of Polynucleotides Through an Aerolysin Nanopore.

Authors:  Chan Cao; Jie Yu; Ya-Qian Wang; Yi-Lun Ying; Yi-Tao Long
Journal:  Anal Chem       Date:  2016-04-29       Impact factor: 6.986

7.  Direct Readout of Single Nucleobase Variations in an Oligonucleotide.

Authors:  Chan Cao; Jie Yu; Meng-Yin Li; Ya-Qian Wang; He Tian; Yi-Tao Long
Journal:  Small       Date:  2017-10-11       Impact factor: 13.281

8.  Nanopore-based detection of circulating microRNAs in lung cancer patients.

Authors:  Yong Wang; Dali Zheng; Qiulin Tan; Michael X Wang; Li-Qun Gu
Journal:  Nat Nanotechnol       Date:  2011-09-04       Impact factor: 39.213

9.  Nanopore sensing of botulinum toxin type B by discriminating an enzymatically cleaved Peptide from a synaptic protein synaptobrevin 2 derivative.

Authors:  Yong Wang; Vedrana Montana; Vladimir Grubišić; Randy F Stout; Vladimir Parpura; Li-Qun Gu
Journal:  ACS Appl Mater Interfaces       Date:  2014-12-29       Impact factor: 9.229

10.  Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis.

Authors:  Alexander L Greninger; Samia N Naccache; Scot Federman; Guixia Yu; Placide Mbala; Vanessa Bres; Doug Stryke; Jerome Bouquet; Sneha Somasekar; Jeffrey M Linnen; Roger Dodd; Prime Mulembakani; Bradley S Schneider; Jean-Jacques Muyembe-Tamfum; Susan L Stramer; Charles Y Chiu
Journal:  Genome Med       Date:  2015-09-29       Impact factor: 11.117
View more
  4 in total

1.  Nanopore Fabrication and Application as Biosensors in Neurodegenerative Diseases.

Authors:  Brian Lenhart; Xiaojun Wei; Zehui Zhang; Xiaoqin Wang; Qian Wang; Chang Liu
Journal:  Crit Rev Biomed Eng       Date:  2020

2.  Lamprey Immune Protein Mediates Apoptosis of Lung Cancer Cells Via the Endoplasmic Reticulum Stress Signaling Pathway.

Authors:  Xiaoping Song; Xiangting Xu; Jiali Lu; Xiaoyuan Chi; Yue Pang; Qingwei Li
Journal:  Front Oncol       Date:  2021-07-07       Impact factor: 6.244

Review 3.  Animal secretory endolysosome channel discovery.

Authors:  Yun Zhang; Qi-Quan Wang; Zhong Zhao; Cheng-Jie Deng
Journal:  Zool Res       Date:  2021-03-18

4.  Sensitive Detection of Single-Nucleotide Polymorphisms by Solid Nanopores Integrated With DNA Probed Nanoparticles.

Authors:  Ling Zhi Wu; Yuan Ye; Zhi Xuan Wang; Die Ma; Li Li; Guo Hao Xi; Bi Qing Bao; Li Xing Weng
Journal:  Front Bioeng Biotechnol       Date:  2021-06-30
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.