Literature DB >> 29989842

How little is known about the role of human FOXP3+ Tregs in tumors.

Tatiana Akimova1, Wayne W Hancock1.   

Abstract

Entities:  

Keywords:  T-regulatory cells; clinical oncology; clinical research; immuno-oncology; immunotherapy

Mesh：

Substances：

Year:  2018        PMID： 29989842      PMCID： PMC6294964          DOI： 10.1080/14728222.2018.1499728

Source DB:  PubMed          Journal:  Expert Opin Ther Targets        ISSN： 1472-8222            Impact factor:   6.902


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  15 in total

1.  Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.

Authors:  Xiaomin Song; Bin Li; Yan Xiao; Chunxia Chen; Qiang Wang; Yujie Liu; Alan Berezov; Chen Xu; Yayi Gao; Zhiyuan Li; Shiaw-Lin Wu; Zheng Cai; Hongtao Zhang; Barry L Karger; Wayne W Hancock; Andrew D Wells; Zhaocai Zhou; Mark I Greene
Journal:  Cell Rep       Date:  2012-06-15       Impact factor: 9.423

Review 2.  Lost in translation: animal models and clinical trials in cancer treatment.

Authors:  Isabella Wy Mak; Nathan Evaniew; Michelle Ghert
Journal:  Am J Transl Res       Date:  2014-01-15       Impact factor: 4.060

Review 3.  FOXP3+ Treg as a therapeutic target for promoting anti-tumor immunity.

Authors:  Theresa L Whiteside
Journal:  Expert Opin Ther Targets       Date:  2018-04-10       Impact factor: 6.902

4.  Human lung tumor FOXP3+ Tregs upregulate four "Treg-locking" transcription factors.

Authors:  Tatiana Akimova; Tianyi Zhang; Dmitri Negorev; Sunil Singhal; Jason Stadanlick; Abhishek Rao; Michael Annunziata; Matthew H Levine; Ulf H Beier; Joshua M Diamond; Jason D Christie; Steven M Albelda; Evgeniy B Eruslanov; Wayne W Hancock
Journal:  JCI Insight       Date:  2017-08-17

5.  Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells.

Authors:  Jorieke H Peters; Hans J P M Koenen; Esther Fasse; Henk J Tijssen; Jan N M Ijzermans; Patricia J T A Groenen; Nicolaas P M Schaap; Jaap Kwekkeboom; Irma Joosten
Journal:  Blood       Date:  2013-08-15       Impact factor: 22.113

6.  Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.

Authors:  Alessia Angelin; Luis Gil-de-Gómez; Satinder Dahiya; Jing Jiao; Lili Guo; Matthew H Levine; Zhonglin Wang; William J Quinn; Piotr K Kopinski; Liqing Wang; Tatiana Akimova; Yujie Liu; Tricia R Bhatti; Rongxiang Han; Benjamin L Laskin; Joseph A Baur; Ian A Blair; Douglas C Wallace; Wayne W Hancock; Ulf H Beier
Journal:  Cell Metab       Date:  2017-04-13       Impact factor: 27.287

7.  Ex vivo analysis of pancreatic cancer-infiltrating T lymphocytes reveals that ENO-specific Tregs accumulate in tumor tissue and inhibit Th1/Th17 effector cell functions.

Authors:  Amedeo Amedei; Elena Niccolai; Marisa Benagiano; Chiara Della Bella; Fabio Cianchi; Paolo Bechi; Antonio Taddei; Lapo Bencini; Marco Farsi; Paola Cappello; Domenico Prisco; Francesco Novelli; Mario Milco D'Elios
Journal:  Cancer Immunol Immunother       Date:  2013-05-03       Impact factor: 6.968

8.  Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function.

Authors:  Yujie Liu; Liqing Wang; Rongxiang Han; Ulf H Beier; Wayne W Hancock
Journal:  PLoS One       Date:  2012-01-11       Impact factor: 3.240

9.  Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity.

Authors:  Liqing Wang; Suresh Kumar; Satinder Dahiya; Feng Wang; Jian Wu; Kheng Newick; Rongxiang Han; Arabinda Samanta; Ulf H Beier; Tatiana Akimova; Tricia R Bhatti; Benjamin Nicholson; Mathew P Kodrasov; Saket Agarwal; David E Sterner; Wei Gu; Joseph Weinstock; Tauseef R Butt; Steven M Albelda; Wayne W Hancock
Journal:  EBioMedicine       Date:  2016-10-15       Impact factor: 8.143

10.  The Different Functional Distribution of "Not Effector" T Cells (Treg/Tnull) in Colorectal Cancer.

Authors:  Elena Niccolai; Federica Ricci; Edda Russo; Giulia Nannini; Giacomo Emmi; Antonio Taddei; Maria Novella Ringressi; Filippo Melli; Manouela Miloeva; Fabio Cianchi; Paolo Bechi; Domenico Prisco; Amedeo Amedei
Journal:  Front Immunol       Date:  2017-12-22       Impact factor: 7.561
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  1 in total

1.  Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells.

Authors:  Yujie Liu; Chunrong Bao; Liqing Wang; Rongxiang Han; Ulf H Beier; Tatiana Akimova; Philip A Cole; Sharon Y R Dent; Wayne W Hancock
Journal:  Cancers (Basel)       Date:  2019-04-18       Impact factor: 6.639
  1 in total

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