Literature DB >> 29984672

Overview of the Recent Advances in Pathophysiology and Treatment for Autism.

Hamidreza Famitafreshi1, Morteza Karimian2.   

Abstract

BACKGROUND &
OBJECTIVE: Autism is a developmental disorder that manifests itself in early childhood. Autism is characterized by inability to acquire social skills, repetitive behaviors and failure of speech and nonverbal communication development. Recent studies have shown that genetic mutations occur in majority of individuals with autism. These mutations cause a variety of disorders that ultimately lead to brain disorders. It is noteworthy that all mutations do not follow the same pattern. They encompass various kinds of mutations. Autism needs to be treated during childhood as untreated patients usually do not progress to the later stages of development. In this regard, many studies have been performed and numerous treatments have been proposed to improve the outcome of this disease.
CONCLUSION: In this review, we have discussed new advancements made in understanding the pathophysiology of autism. Furthermore, we have also discussed new treatments which have been proposed and have successfully translated affected children. Overall, it is concluded that new advances have largely helped these patients. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Autism; brain stimulation; gut-brain; immune system; mutation; nutrition.

Mesh:

Year:  2018        PMID: 29984672     DOI: 10.2174/1871527317666180706141654

Source DB:  PubMed          Journal:  CNS Neurol Disord Drug Targets        ISSN: 1871-5273            Impact factor:   4.388


  7 in total

1.  Correlation Between CD133+ Stem Cells and Clinical Improvement in Patients with Autism Spectrum Disorders Treated with Intrathecal Bone Marrow-derived Mononuclear Cells.

Authors:  Laura Villarreal-Martinez; Laura Elia MartÍnez-Garza; Iram Pablo Rodriguez-Sanchez; Neri Alvarez-Villalobos; Fernando Guzman-Gallardo; Sulia Pope-Salazar; Cynthia Salinas-Silva; Maria Guadalupe Cepeda-Cepeda; Alejandra Garza-Bedolla; Irving Armando Dominguez-Varela; Daniel Zacarias Villarreal-Martinez; Jose Humberto Treviño-Villarreal; David Gomez-Almaguer
Journal:  Innov Clin Neurosci       Date:  2022 Apr-Jun

Review 2.  Research Progress on the Role of Vitamin D in Autism Spectrum Disorder.

Authors:  Jing Wang; Haoyu Huang; Chunming Liu; Yangping Zhang; Wenjuan Wang; Zhuo Zou; Lei Yang; Xuemei He; Jinting Wu; Jing Ma; Yun Liu
Journal:  Front Behav Neurosci       Date:  2022-05-10       Impact factor: 3.617

3.  Bioinformatics analysis of genomic and immune infiltration patterns in autism spectrum disorder.

Authors:  Ru-Qiong Wei; Wen-Liang Guo; Yin-Teng Wu; Raquel Alarcòn Rodrìguez; Marìa Del Mar Requena Mullor; Yu-Chang Gui; Jian-Wen Xu
Journal:  Ann Transl Med       Date:  2022-09

Review 4.  The Role of the Gut Microbiota and the Immune System in the Development of Autism.

Authors:  Rayan M Lungba; Seyad Zulficar Ali Khan; Uvie Ajibawo-Aganbi; Maria V Perez Bastidas; Swathi Veliginti; Sania Saleem; Ivan Cancarevic
Journal:  Cureus       Date:  2020-10-28

5.  Communication and Language Skills of Autistic Spectrum Disorders in Children and Their Parents' Emotions.

Authors:  Amela Ibrahimagic; Nedim Patkovic; Bojan Radic; Selmir Hadzic
Journal:  Mater Sociomed       Date:  2021-12

6.  Application of Three-Dimensional Pseudocontinuous Arterial Spin Labeling Perfusion Imaging in the Brains of Children With Autism.

Authors:  Shilong Tang; Xianfan Liu; Qiying Ran; Lisha Nie; Lan Wu; Zhengxia Pan; Ling He
Journal:  Front Neurol       Date:  2022-02-23       Impact factor: 4.003

Review 7.  G Protein-Coupled Receptor Heteromers as Putative Pharmacotherapeutic Targets in Autism.

Authors:  Jon DelaCuesta-Barrutia; Olga Peñagarikano; Amaia M Erdozain
Journal:  Front Cell Neurosci       Date:  2020-10-30       Impact factor: 5.505

  7 in total

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