Vikneswary Batumalai1, Jesmin Shafiq2, Gabriel Gabriel2, Timothy P Hanna3, Geoff P Delaney4, Michael Barton4. 1. Department of Radiation Oncology, South Western Sydney Local Health District, New South Wales, Australia; Collaboration for Cancer Outcomes Research and Evaluation, Ingham Institute for Applied Medical Research, New South Wales, Australia; South Western Clinical School, University of New South Wales, New South Wales, Australia. Electronic address: vikneswary.batumalai@health.nsw.gov.au. 2. Collaboration for Cancer Outcomes Research and Evaluation, Ingham Institute for Applied Medical Research, New South Wales, Australia; South Western Clinical School, University of New South Wales, New South Wales, Australia. 3. Collaboration for Cancer Outcomes Research and Evaluation, Ingham Institute for Applied Medical Research, New South Wales, Australia; Division of Cancer Care and Epidemiology, Cancer Research Institute, Queen's University, Ontario, Canada. 4. Department of Radiation Oncology, South Western Sydney Local Health District, New South Wales, Australia; Collaboration for Cancer Outcomes Research and Evaluation, Ingham Institute for Applied Medical Research, New South Wales, Australia; South Western Clinical School, University of New South Wales, New South Wales, Australia.
Abstract
BACKGROUND AND PURPOSE: Despite evidence of the benefits of radiotherapy (RT) in the treatment of cancer patients, its underutilisation has been reported for various tumour sites. The aim of this study was to estimate survival shortfall, 'years of potential life lost' (YPLL) and 'disability-adjusted life years lost' (DALY) to demonstrate the impact of radiotherapy underutilisation in Australia. MATERIALS AND METHODS: Optimal and actual RT utilisation (RTU) was compared to assess RT underutilisation to estimate 5-year overall survival shortfall using 2006 data from New South Wales (NSW) for 26 common tumour sites. 5-year overall survival shortfall is defined as number of people not surviving for 5-years due to RT underutilisation [=benefit proportion × shortfall [(optimal-actual RTU)/optimal RTU] proportion × No. of new cases]. YPLL = survival shortfall × estimated years of life lost per person (overall life expectancy - median age at death for specific cancer). DALY = (Years lived with disability + Years of life lost) × survival shortfall. RESULTS: The total number of new cases with cancer in 2006 in NSW was 20,741. Optimal RTU was 48% while actual RTU was 26%, resulting in estimated of 411 deaths due to underutilisation. Each death resulted in an average of 10.4 YPLL and 17.5 DALY. It was estimated RT underutilisation resulted in a total of 4,289 YPLL and 7,192 DALY overall. CONCLUSION: This study illustrates the value of considering different mortality statistics, which include measures of the burden of cancer deaths on both the population and patients. Crown
BACKGROUND AND PURPOSE: Despite evidence of the benefits of radiotherapy (RT) in the treatment of cancerpatients, its underutilisation has been reported for various tumour sites. The aim of this study was to estimate survival shortfall, 'years of potential life lost' (YPLL) and 'disability-adjusted life years lost' (DALY) to demonstrate the impact of radiotherapy underutilisation in Australia. MATERIALS AND METHODS: Optimal and actual RT utilisation (RTU) was compared to assess RT underutilisation to estimate 5-year overall survival shortfall using 2006 data from New South Wales (NSW) for 26 common tumour sites. 5-year overall survival shortfall is defined as number of people not surviving for 5-years due to RT underutilisation [=benefit proportion × shortfall [(optimal-actual RTU)/optimal RTU] proportion × No. of new cases]. YPLL = survival shortfall × estimated years of life lost per person (overall life expectancy - median age at death for specific cancer). DALY = (Years lived with disability + Years of life lost) × survival shortfall. RESULTS: The total number of new cases with cancer in 2006 in NSW was 20,741. Optimal RTU was 48% while actual RTU was 26%, resulting in estimated of 411 deaths due to underutilisation. Each death resulted in an average of 10.4 YPLL and 17.5 DALY. It was estimated RT underutilisation resulted in a total of 4,289 YPLL and 7,192 DALY overall. CONCLUSION: This study illustrates the value of considering different mortality statistics, which include measures of the burden of cancer deaths on both the population and patients. Crown
Authors: Wei Liu; Alissa Liu; Jessica Chan; R Gabriel Boldt; Pablo Munoz-Schuffenegger; Alexander V Louie Journal: Transl Lung Cancer Res Date: 2019-09
Authors: Bróna Nic Giolla Easpaig; Gaston Arnolda; Yvonne Tran; Mia Bierbaum; Klay Lamprell; Geoffrey P Delaney; Winston Liauw; Renuka Chittajallu; Teresa Winata; Robyn L Ward; David C Currow; Ian Olver; Jonathan Karnon; Johanna Westbrook; Jeffrey Braithwaite Journal: BMJ Open Date: 2019-10-10 Impact factor: 2.692
Authors: Wee Loon Ong; Norah Finn; Luc Te Marvelde; Colin Hornby; Roger L Milne; Gerard G Hanna; Graham Pitson; Hany Elsaleh; Jeremy L Millar; Farshad Foroudi Journal: J Med Imaging Radiat Oncol Date: 2022-03-31 Impact factor: 1.667