Literature DB >> 29973758

First Ever Robotic Stage One ALPPS Procedure in India: for Colorectal Liver Metastases.

Jagadeesh Krishnamurthy1, Adithya V Naragund1, Basant Mahadevappa1.   

Abstract

Twenty five percent of total liver volume (TLV) is considered as the ideal functional liver remnant (FLR) in major liver resections. In patients with macro-vesicular steatosis, early cirrhosis, and post-neoadjuvant chemotherapy (NACT), hepatocellular injury is common. In such instances, up to 40% of FLR may be required. So in cases of marginal FLR, pre-operative portal vein (PV) embolization or two-stage hepatectomy with PV occlusion is used. Both of which take up to 14 weeks between stages and 30% of patients fail to reach the second resection either due to inadequate FLR growth or disease progression. Associated liver partition and portal vein ligation (ALPPS) procedure has become the gold standard for those cases. A 57-year-old male presented with rectosigmoid growth + multiple right liver and segment 4B metastases. Post-NACT MRI showed interval progression of lesions. Preoperative CT (computed tomography) volumetric scan showed a FLR/TLV (future liver remnant/total liver volume) of 22%. Since patient received 10 cycles of NACT, ALPPS procedure was planned ahead of direct liver resection. Robotic ALPPS stage 1 sparing left lateral segment and 4A + anterior resection was done. We transected the parenchyma between the FLR and the diseased part of the liver with concomitant right portal vein ligation done robotically. CT abdomen done on POD7 showed hypertrophied left lateral segment. Second stage was performed on the eighth post-operative day with FLR/TLV increasing to 37%. Robotic ALPPS procedure for stage one is a safe and feasible technique in experienced centers with advanced robotic skills.

Entities:  

Keywords:  Colorectal liver metastasis; FLR hypertrophy; Minimal access; Robotic ALPPS

Year:  2017        PMID: 29973758      PMCID: PMC6014955          DOI: 10.1007/s12262-017-1713-0

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  7 in total

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4.  Preoperative portal vein embolization for major liver resection: a meta-analysis.

Authors:  Adel Abulkhir; Paolo Limongelli; Andrew J Healey; Osama Damrah; Paul Tait; James Jackson; Nagy Habib; Long R Jiao
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Review 6.  Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): a new strategy to increase resectability in liver surgery.

Authors:  Guan-Qi Zhang; Zhi-Wei Zhang; Wan-Yee Lau; Xiao-Ping Chen
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Review 7.  An updated systematic review of the evolution of ALPPS and evaluation of its advantages and disadvantages in accordance with current evidence.

Authors:  Yu-Long Cai; Pei-Pei Song; Wei Tang; Nan-Sheng Cheng
Journal:  Medicine (Baltimore)       Date:  2016-06       Impact factor: 1.889

  7 in total
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Review 1.  Associated liver partition and portal vein ligation for staged hepatectomy: a review.

Authors:  Kai Siang Chan; Jee Keem Low; Vishal G Shelat
Journal:  Transl Gastroenterol Hepatol       Date:  2020-07-05

Review 2.  A better route to ALPPS: minimally invasive vs open ALPPS.

Authors:  Kawka Michal; Mak Sau; Gall M H Tamara; Jiao R Long
Journal:  Surg Endosc       Date:  2020-04-09       Impact factor: 4.584

  2 in total

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