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Literature DB >> 29969566

Synthesis of 8-Hydroxygeraniol.

Francesca M Ippoliti¹, Joyann S Barber¹, Yi Tang¹, Neil K Garg¹.

Abstract

An operationally simple protocol for the conversion of geranyl acetate to 8-hydroxygeraniol is reported. The convenient two-step procedure relies on an efficient, chemo- and regioselective SeO2-promoted oxidation, followed by straightforward deacetylation. This facile means to prepare 8-hydroxygeraniol is expected to enable biosynthetic studies pertaining to thousands of monoterpene indole alkaloids.

Entities: Chemical Disease Species

Mesh：

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Year: 2018 PMID： 29969566 PMCID： PMC6508077 DOI： 10.1021/acs.joc.8b01544

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

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