Literature DB >> 29968185

Medication Allergy and Adverse Drug Reaction Documentation Discrepancies in an Urban, Academic Emergency Department.

Eric S Kiechle1, Colleen M McKenna2, Hannah Carter2, Alexander Zeymo3, Bradley W Gelfand2, Lindsey M DeGeorge4, Diane A Sauter4, Maryann Mazer-Amirshahi4,2.   

Abstract

INTRODUCTION: Medication histories, including knowledge of allergies and adverse drug reactions (ADRs), are a nationally recognized quality measure. Medication histories in the emergency department (ED) are often inaccurate or incomplete. Our objective was to determine the prevalence and nature of medication allergy and ADR discrepancies in an urban ED.
METHODS: This was a prospective observational descriptive study, enrolling a convenience sample of adults over 7 months at a single academic urban ED. Trained personnel recorded patient demographics and number of daily medications. Patients listed any prior drug allergies or non-allergic ADRs. Following the ED encounter, the patients' self-reported allergies and ADRs were compared to the electronic medical record (EMR) to identify and describe discrepancies.
RESULTS: A sample of 1014 patients, predominantly black (81%), female (60%), and in the 18- to 59-year-old range (69%), was recruited. Most patients were taking at least one daily medication (74%). Three hundred fifteen patients reported at least one allergy (31%), and 252 (25%) at least one ADR. Four hundred sixteen patients (41%) had a discrepancy between their self-report of allergy or ADR and the EMR. Omissions were the most frequent discrepancy. Full descriptions of allergies or ADR were present in 18.4% of charts. Fifty-seven patients (5.6%) were administered a medication which could have interacted with a documented allergy or ADR; none of the allergy EMR records were updated to reflected this.
CONCLUSIONS: In this cross-sectional ED study, drug allergies and ADRs were both highly prevalent. There were significant discrepancies in documentation of allergies and ADRs between patient self-report and the EMR.

Entities:  

Keywords:  Adverse drug reactions; Allergic reactions; Emergency department; Medication history

Mesh:

Year:  2018        PMID: 29968185      PMCID: PMC6242795          DOI: 10.1007/s13181-018-0671-7

Source DB:  PubMed          Journal:  J Med Toxicol        ISSN: 1556-9039


  17 in total

Review 1.  Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review.

Authors:  Vincent C Tam; Sandra R Knowles; Patricia L Cornish; Nowell Fine; Romina Marchesano; Edward E Etchells
Journal:  CMAJ       Date:  2005-08-30       Impact factor: 8.262

2.  Drug history taking and the identification of drug related problems in an accident and emergency department.

Authors:  I Akwagyriam; L I Goodyer; L Harding; S Khakoo; H Millington
Journal:  J Accid Emerg Med       Date:  1996-05

3.  Best possible medication history in the emergency department: comparing pharmacy technicians and pharmacists.

Authors:  Rochelle Johnston; Lauza Saulnier; Odette Gould
Journal:  Can J Hosp Pharm       Date:  2010-09

Review 4.  Epidemiology and risk factors for drug allergy.

Authors:  Bernard Y-H Thong; Teck-Choon Tan
Journal:  Br J Clin Pharmacol       Date:  2011-05       Impact factor: 4.335

5.  Medication history taking in emergency department triage is inaccurate and incomplete.

Authors:  Maryann Mazer; Francis Deroos; Judd E Hollander; Christine McCusker; Nicholas Peacock; Jeanmarie Perrone
Journal:  Acad Emerg Med       Date:  2010-12-22       Impact factor: 3.451

6.  Factors related to errors in medication prescribing.

Authors:  T S Lesar; L Briceland; D S Stein
Journal:  JAMA       Date:  1997 Jan 22-29       Impact factor: 56.272

7.  Emergency department medication lists are not accurate.

Authors:  Selin Caglar; Philip L Henneman; Fidela S Blank; Howard A Smithline; Elizabeth A Henneman
Journal:  J Emerg Med       Date:  2008-10-01       Impact factor: 1.484

8.  The use of penicillin skin testing to assess the prevalence of penicillin allergy in an emergency department setting.

Authors:  Ali S Raja; Christopher J Lindsell; Jonathan A Bernstein; Christopher D Codispoti; Joseph J Moellman
Journal:  Ann Emerg Med       Date:  2009-02-13       Impact factor: 5.721

9.  Recording of drug allergies: are we doing enough?

Authors:  Anna Radford; Shabnam Undre; Nawar A Alkhamesi; Sir Ara W Darzi
Journal:  J Eval Clin Pract       Date:  2007-02       Impact factor: 2.431

10.  Effect of medication reconciliation on unintentional medication discrepancies in acute hospital admissions of elderly adults: a multicenter study.

Authors:  Patricia M L A van den Bemt; Erica M van der Schrieck-de Loos; Christien van der Linden; Annemiek M L J Theeuwes; Albert G Pol
Journal:  J Am Geriatr Soc       Date:  2013-07-19       Impact factor: 5.562

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  2 in total

Review 1.  The Use of Electronic Health Records to Study Drug-Induced Hypersensitivity Reactions from 2000 to 2021: A Systematic Review.

Authors:  Fatima Bassir; Sheril Varghese; Liqin Wang; Yen Po Chin; Li Zhou
Journal:  Immunol Allergy Clin North Am       Date:  2022-03-31       Impact factor: 3.152

2.  An Incomplete Medical Record: Transfer of Care From Emergency Medical Services to the Emergency Department.

Authors:  Jeffrey S Lubin; Akash Shah
Journal:  Cureus       Date:  2022-02-21
  2 in total

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