Literature DB >> 299656

Are double minutes chromosomes?

P E Barker1, T C Hsu.   

Abstract

Double minutes of a human breast cancer cell line revealed no centromeres by Cd banding. They cluster at the periphery of metaphase plates, usually encased in a matrix material. They move in anaphase passively with the chromosomes by attaching to the sides or ends of the chromosomes. The two "sister minutes" move to the same pole without separation. Such anomalous mitotic behavior suggests that double minutes are not chromosomes.

Entities:  

Mesh：

Year:  1978        PMID： 299656     DOI： 10.1016/0014-4827(78)90391-9

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN： 0014-4827            Impact factor:   3.905


  10 in total

Review 1.  Double minutes, cytogenetic equivalents of gene amplification, in human neoplasia - a review.

Authors:  Erich Gebhart
Journal:  Clin Transl Oncol       Date:  2005-12       Impact factor: 3.405

2.  DNA content and structure of (double) minutes of a methotrexate-resistant cell line.

Authors:  A P Jongsma; W A Duijndam; P Borst
Journal:  Histochemistry       Date:  1989

3.  Analysis of the replication mode of double minutes using the PCC technique combined with BrdUrd labeling.

Authors:  S Takayama; Y Uwaike
Journal:  Chromosoma       Date:  1988-11       Impact factor: 4.316

4.  Behavior of the chromosome core in mitosis and meiosis.

Authors:  K L Satya-Prakash; T C Hsu; S Pathak
Journal:  Chromosoma       Date:  1980       Impact factor: 4.316

Review 5.  Cytogenetic abnormalities in cancer: with special emphasis on tumor heterogeneity.

Authors:  S Pathak
Journal:  Cancer Metastasis Rev       Date:  1990-02       Impact factor: 9.264

Review 6.  Extrachromosomal DNA amplifications in cancer.

Authors:  Eunhee Yi; Rocío Chamorro González; Anton G Henssen; Roel G W Verhaak
Journal:  Nat Rev Genet       Date:  2022-08-11       Impact factor: 59.581

7.  Gene amplification in a mouse embryo? Double minutes in cell lines independently derived from a Mus musculus X M. caroli fetus.

Authors:  J A Graves
Journal:  Chromosoma       Date:  1984       Impact factor: 4.316

8.  Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.

Authors:  R J Kaufman; P C Brown; R T Schimke
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

9.  Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes.

Authors:  J Barsoum; A Varshavsky
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

10.  Ultrastructure of double minutes from a human tumor cell line.

Authors:  P E Barker; E Stubblefield
Journal:  J Cell Biol       Date:  1979-12       Impact factor: 10.539
  10 in total

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