Literature DB >> 2996336

Determination of the parental origin of sex-chromosome monosomy using restriction fragment length polymorphisms.

T Hassold, E Kumlin, N Takaesu, M Leppert.   

Abstract

The parental origin of the single X chromosome in sex-chromosome monosomy was evaluated by comparing restriction fragment length polymorphisms (RFLPs) of 10 spontaneous aborted 45,X conceptions with those of their parents. Seven X-linked marker loci were used, and we were able to specify the origin of the X in nine cases, with six being maternally and three paternally derived. These results demonstrate the efficiency of the technique and show that the single X chromosome in 45,X spontaneous abortions can be derived from either parent.

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Year:  1985        PMID： 2996336      PMCID： PMC1684699     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  17 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  Monosomy 21 in a human spontaneous abortus. Morphogenetic disturbances and phenotype at the cellular level.

Authors:  A M Kuliev; K N Grinberg; V I Kukharenko; V P Kulazenko; E A Bogomazov
Journal:  Hum Genet       Date:  1977-09-22       Impact factor: 4.132

3.  Monosomy X: a chromosomal anomaly associated with young maternal age.

Authors:  D Warburton; J Kline; Z Stein; M Susser
Journal:  Lancet       Date:  1980-01-26       Impact factor: 79.321

4.  A strategy to reveal high-frequency RFLPs along the human X chromosome.

Authors:  J Aldridge; L Kunkel; G Bruns; U Tantravahi; M Lalande; T Brewster; E Moreau; M Wilson; W Bromley; T Roderick
Journal:  Am J Hum Genet       Date:  1984-05       Impact factor: 11.025

5.  Genetic mapping of the human X chromosome by using restriction fragment length polymorphisms.

Authors:  D Drayna; K Davies; D Hartley; J L Mandel; G Camerino; R Williamson; R White
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

6.  The distribution of chromosomal genotypes associated with Turner's syndrome: livebirth prevalence rates and evidence for diminished fetal mortality and severity in genotypes associated with structural X abnormalities or mosaicism.

Authors:  E B Hook; D Warburton
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

7.  A cytogenetic study of 1000 spontaneous abortions.

Authors:  T Hassold; N Chen; J Funkhouser; T Jooss; B Manuel; J Matsuura; A Matsuyama; C Wilson; J A Yamane; P A Jacobs
Journal:  Ann Hum Genet       Date:  1980-10       Impact factor: 1.670

8.  Human triploidy: relationship between parental origin of the additional haploid complement and development of partial hydatidiform mole.

Authors:  P A Jacobs; A E Szulman; J Funkhouser; J S Matsuura; C C Wilson
Journal:  Ann Hum Genet       Date:  1982-07       Impact factor: 1.670

9.  Chromosomal abnormalities in human sperm: comparisons among four healthy men.

Authors:  B Brandriff; L Gordon; L Ashworth; G Watchmaker; A Carrano; A Wyrobek
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  The chromosome constitution of 1000 human spermatozoa.

Authors:  R H Martin; W Balkan; K Burns; A W Rademaker; C C Lin; N L Rudd
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132
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  11 in total

1.  Oocyte selection: a new model for the maternal-age dependence of Down syndrome.

Authors:  C J Zheng; B Byers
Journal:  Hum Genet       Date:  1992 Sep-Oct       Impact factor: 4.132

2.  Nondisjunction of chromosome 21: comparisons of cytogenetic and molecular studies of the meiotic stage and parent of origin.

Authors:  B J Lorber; M Grantham; J Peters; H F Willard; T J Hassold
Journal:  Am J Hum Genet       Date:  1992-12       Impact factor: 11.025

3.  Molecular studies of parental origin and mosaicism in 45,X conceptuses.

Authors:  T Hassold; D Pettay; A Robinson; I Uchida
Journal:  Hum Genet       Date:  1992-08       Impact factor: 4.132

4.  Analysis of the origin of Turner's syndrome using polymorphic DNA probes.

Authors:  S A Loughlin; A Redha; J McIver; E Boyd; A Carothers; J M Connor
Journal:  J Med Genet       Date:  1991-03       Impact factor: 6.318

5.  The parental origin of the single X chromosome in Turner syndrome: lack of correlation with parental age or clinical phenotype.

Authors:  A Mathur; L Stekol; D Schatz; N K MacLaren; M L Scott; B Lippe
Journal:  Am J Hum Genet       Date:  1991-04       Impact factor: 11.025

6.  Trisomy 21: association between reduced recombination and nondisjunction.

Authors:  S L Sherman; N Takaesu; S B Freeman; M Grantham; C Phillips; R D Blackston; P A Jacobs; A E Cockwell; V Freeman; I Uchida
Journal:  Am J Hum Genet       Date:  1991-09       Impact factor: 11.025

7.  Mosaicism in 45,X Turner syndrome: does survival in early pregnancy depend on the presence of two sex chromosomes?

Authors:  K R Held; S Kerber; E Kaminsky; S Singh; P Goetz; E Seemanova; H W Goedde
Journal:  Hum Genet       Date:  1992-01       Impact factor: 4.132

8.  Cytogenetic analysis of early human abortuses after preparation of chromosomes directly from chorionic villi.

Authors:  I Hansmann; I Bartels; I Schübbe
Journal:  Hum Genet       Date:  1986-02       Impact factor: 4.132

9.  Cytogenetic and molecular analysis of sex-chromosome monosomy.

Authors:  T Hassold; F Benham; M Leppert
Journal:  Am J Hum Genet       Date:  1988-04       Impact factor: 11.025

10.  Cytogenetic and molecular studies of trisomy 13.

Authors:  T Hassold; P A Jacobs; M Leppert; M Sheldon
Journal:  J Med Genet       Date:  1987-12       Impact factor: 6.318
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