Martin Benka Wallén1, Maria Hagströmer1,2, David Conradsson1,2, Kimmo Sorjonen3, Erika Franzén1,2. 1. 1 Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. 2. 2 Function Area Occupational Therapy & Physiotherapy, Allied Health Professionals Function, Karolinska University Hospital, Stockholm, Sweden. 3. 3 Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Abstract
OBJECTIVES: : To determine long-term effects of a highly challenging training program in people with Parkinson's disease, as well as describe how initially observed improvements of the program deteriorated over time. DESIGN: : Long-term follow-up of previously reported outcomes at 10 weeks of a randomized controlled trial. SETTING: : University hospital setting. PARTICIPANTS:: One-hundred elderly with mild-to-moderate (Hoehn and Yahr 2-3) Parkinson's disease. INTERVENTIONS: : Participants in the training group ( n = 51) received 10 weeks (three times/week) of balance and gait exercises, incorporating dual-tasks, while the control group ( n = 49) received care as usual. MAIN OUTCOME MEASURES:: Balance control (Mini-Balance Evaluation System Test (Mini-BESTest)) and gait velocity. Mixed-design analyses of variance were used to determine potential training effects at 6- and 12-month follow-up, and piecewise regression models predicted the rate of deterioration. RESULTS: : Seventy-six participants were included at final follow-up. No significant ( P > .05) between-group differences remained at either 6 or 12 months following the intervention. The mean Mini-BESTest scores of the training and control group were 19.9 (SD 4.4) and 18.6 (SD 4.3), respectively, at the 12-month follow-up. Gait speed was 1.2 (SD 0.2) m/s in both groups at 12 months. The training group showed a larger deterioration rate per month in balance performance (0.21 point) and gait velocity (0.65 cm/s) than controls ( P < .05). CONCLUSION: : These results suggest that training effects diminish within 6 months after balance training, implying that the program may need to be repeated regularly.
RCT Entities:
OBJECTIVES: : To determine long-term effects of a highly challenging training program in people with Parkinson's disease, as well as describe how initially observed improvements of the program deteriorated over time. DESIGN: : Long-term follow-up of previously reported outcomes at 10 weeks of a randomized controlled trial. SETTING: : University hospital setting. PARTICIPANTS:: One-hundred elderly with mild-to-moderate (Hoehn and Yahr 2-3) Parkinson's disease. INTERVENTIONS: : Participants in the training group ( n = 51) received 10 weeks (three times/week) of balance and gait exercises, incorporating dual-tasks, while the control group ( n = 49) received care as usual. MAIN OUTCOME MEASURES:: Balance control (Mini-Balance Evaluation System Test (Mini-BESTest)) and gait velocity. Mixed-design analyses of variance were used to determine potential training effects at 6- and 12-month follow-up, and piecewise regression models predicted the rate of deterioration. RESULTS: : Seventy-six participants were included at final follow-up. No significant ( P > .05) between-group differences remained at either 6 or 12 months following the intervention. The mean Mini-BESTest scores of the training and control group were 19.9 (SD 4.4) and 18.6 (SD 4.3), respectively, at the 12-month follow-up. Gait speed was 1.2 (SD 0.2) m/s in both groups at 12 months. The training group showed a larger deterioration rate per month in balance performance (0.21 point) and gait velocity (0.65 cm/s) than controls ( P < .05). CONCLUSION: : These results suggest that training effects diminish within 6 months after balance training, implying that the program may need to be repeated regularly.
Entities:
Keywords:
Dual-task; Parkinson’s disease; exercise; gait; postural control
Authors: Kaleen M Lavin; Paul M Coen; Liliana C Baptista; Margaret B Bell; Devin Drummer; Sara A Harper; Manoel E Lixandrão; Jeremy S McAdam; Samia M O'Bryan; Sofhia Ramos; Lisa M Roberts; Rick B Vega; Bret H Goodpaster; Marcas M Bamman; Thomas W Buford Journal: Compr Physiol Date: 2022-03-09 Impact factor: 8.915
Authors: Jacqueline A Osborne; Rachel Botkin; Cristina Colon-Semenza; Tamara R DeAngelis; Oscar G Gallardo; Heidi Kosakowski; Justin Martello; Sujata Pradhan; Miriam Rafferty; Janet L Readinger; Abigail L Whitt; Terry D Ellis Journal: Phys Ther Date: 2022-04-01
Authors: Tamine T C Capato; Nienke M de Vries; Joanna IntHout; Egberto R Barbosa; Jorik Nonnekes; Bastiaan R Bloem Journal: J Parkinsons Dis Date: 2020 Impact factor: 5.568