Literature DB >> 29953873

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.

Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather M Feldman, Hsin-Lan Wen, Jay Penney, Hugh P Cam, Elizabeta Gjoneska, Waseem K Raja, Jemmie Cheng, Richard Rueda, Oleg Kritskiy, Fatema Abdurrob, Zhuyu Peng, Blerta Milo, Chung Jong Yu, Sara Elmsaouri, Dilip Dey, Tak Ko, Bruce A Yankner, Li-Huei Tsai.   

Abstract

Entities:  

Year:  2018        PMID： 29953873      PMCID： PMC6048952          DOI： 10.1016/j.neuron.2018.06.011

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


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  45 in total

1.  CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks.

Authors:  Eric Deneault; Muhammad Faheem; Sean H White; Deivid C Rodrigues; Song Sun; Wei Wei; Alina Piekna; Tadeo Thompson; Jennifer L Howe; Leon Chalil; Vickie Kwan; Susan Walker; Peter Pasceri; Frederick P Roth; Ryan Kc Yuen; Karun K Singh; James Ellis; Stephen W Scherer
Journal:  Elife       Date:  2019-02-12       Impact factor: 8.140

Review 2.  Exploring mitochondrial cholesterol signalling for therapeutic intervention in neurological conditions.

Authors:  Radha Desai; Michelangelo Campanella
Journal:  Br J Pharmacol       Date:  2019-08-09       Impact factor: 8.739

3.  Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions.

Authors:  Benedetta Assetta; Changyong Tang; Jing Bian; Ryan O'Rourke; Kevin Connolly; Thomas Brickler; Sundari Chetty; Yu-Wen Alvin Huang
Journal:  J Vis Exp       Date:  2020-11-09       Impact factor: 1.355

4.  A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance.

Authors:  Hongsheng Zhang; Wenbing Chen; Zhibing Tan; Lei Zhang; Zhaoqi Dong; Wanpeng Cui; Kai Zhao; Hongsheng Wang; Hongyang Jing; Rangjuan Cao; Chae Kim; Jiri G Safar; Wen-Cheng Xiong; Lin Mei
Journal:  J Neurosci       Date:  2020-05-26       Impact factor: 6.167

Review 5.  Microglia as Dynamic Cellular Mediators of Brain Function.

Authors:  Elizabeth C Wright-Jin; David H Gutmann
Journal:  Trends Mol Med       Date:  2019-10-06       Impact factor: 11.951

Review 6.  Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease.

Authors:  Tiantian Guo; Denghong Zhang; Yuzhe Zeng; Timothy Y Huang; Huaxi Xu; Yingjun Zhao
Journal:  Mol Neurodegener       Date:  2020-07-16       Impact factor: 14.195

Review 7.  Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery.

Authors:  Arun Sharma; Samuel Sances; Michael J Workman; Clive N Svendsen
Journal:  Cell Stem Cell       Date:  2020-03-05       Impact factor: 24.633

Review 8.  A brief history of human disease genetics.

Authors:  Melina Claussnitzer; Judy H Cho; Rory Collins; Nancy J Cox; Emmanouil T Dermitzakis; Matthew E Hurles; Sekar Kathiresan; Eimear E Kenny; Cecilia M Lindgren; Daniel G MacArthur; Kathryn N North; Sharon E Plon; Heidi L Rehm; Neil Risch; Charles N Rotimi; Jay Shendure; Nicole Soranzo; Mark I McCarthy
Journal:  Nature       Date:  2020-01-08       Impact factor: 49.962

9.  A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation.

Authors:  Alexandra Grubman; Gabriel Chew; John F Ouyang; Guizhi Sun; Xin Yi Choo; Catriona McLean; Rebecca K Simmons; Sam Buckberry; Dulce B Vargas-Landin; Daniel Poppe; Jahnvi Pflueger; Ryan Lister; Owen J L Rackham; Enrico Petretto; Jose M Polo
Journal:  Nat Neurosci       Date:  2019-12       Impact factor: 24.884

10.  Long-term maturation of human cortical organoids matches key early postnatal transitions.

Authors:  Aaron Gordon; Se-Jin Yoon; Stephen S Tran; Christopher D Makinson; Jin Young Park; Jimena Andersen; Alfredo M Valencia; Steve Horvath; Xinshu Xiao; John R Huguenard; Sergiu P Pașca; Daniel H Geschwind
Journal:  Nat Neurosci       Date:  2021-02-22       Impact factor: 24.884
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