Literature DB >> 29952642

Sugammadex: Efficacy and Practicality in the Dental Office.

Stephen Goetz1, Benjamin Pritts1, Bryant Cornelius2.   

Abstract

Sugammadex is a novel drug capable of reversing paralysis induced by the common steroidal nondepolarizing neuromuscular blocking drugs, rocuronium and vecuronium. Reversal is complete at any depth of blockade dependent on the dose of sugammadex administered. This allows rocuronium to be used as a rescue agent in scenarios where succinylcholine is contraindicated. Sugammadex is considered a safe drug with minimal side effects compared with traditional reversal with neostigmine and glycopyrrolate. This article features a case report where succinylcholine was undesirable and rapid reversal of paralysis with sugammadex was used during general anesthesia for dentistry.

Entities:  

Keywords:  Paralysis; Reversal; Rocuronium; Sugammadex

Mesh:

Substances:

Year:  2018        PMID: 29952642      PMCID: PMC6022787          DOI: 10.2344/anpr-65-03-03

Source DB:  PubMed          Journal:  Anesth Prog        ISSN: 0003-3006


  20 in total

1.  Onset and duration of action of rocuronium--from tracheal intubation, through intense block to complete recovery.

Authors:  P Schultz; M Ibsen; D Østergaard; L T Skovgaard
Journal:  Acta Anaesthesiol Scand       Date:  2001-05       Impact factor: 2.105

2.  Comparison of intubating conditions after administration of Org 9246 (rocuronium) and suxamethonium.

Authors:  R Cooper; R K Mirakhur; R S Clarke; Z Boules
Journal:  Br J Anaesth       Date:  1992-09       Impact factor: 9.166

Review 3.  Case scenario: perianesthetic management of laryngospasm in children.

Authors:  Gilles A Orliaguet; Olivier Gall; Georges L Savoldelli; Vincent Couloigner
Journal:  Anesthesiology       Date:  2012-02       Impact factor: 7.892

Review 4.  Current evidence for the use of sugammadex in children.

Authors:  Joseph D Tobias
Journal:  Paediatr Anaesth       Date:  2016-11-17       Impact factor: 2.556

Review 5.  Efficacy and safety of sugammadex compared to neostigmine for reversal of neuromuscular blockade: a meta-analysis of randomized controlled trials.

Authors:  Michele Carron; Francesco Zarantonello; Paola Tellaroli; Carlo Ori
Journal:  J Clin Anesth       Date:  2016-08-04       Impact factor: 9.452

6.  Intramuscular rocuronium in infants and children. Dose-ranging and tracheal intubating conditions.

Authors:  L M Reynolds; M Lau; R Brown; A Luks; D M Fisher
Journal:  Anesthesiology       Date:  1996-08       Impact factor: 7.892

7.  Comparison of sugammadex and conventional reversal on postoperative nausea and vomiting: a randomized, blinded trial.

Authors:  Onur Koyuncu; Selim Turhanoglu; Cagla Ozbakis Akkurt; Murat Karcıoglu; Mustafa Ozkan; Cahit Ozer; Daniel I Sessler; Alparslan Turan
Journal:  J Clin Anesth       Date:  2014-12-24       Impact factor: 9.452

Review 8.  Dental treatment under general anesthesia: a useful procedure in the third millennium? (l).

Authors:  María del Patrocinio Vargas Román; Sonia Rodríguez Bermudo; Guillermo Machuca Portillo
Journal:  Med Oral       Date:  2003 Mar-Apr

9.  Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.

Authors:  Chingmuh Lee; Jonathan S Jahr; Keith A Candiotti; Brian Warriner; Mark H Zornow; Mohamed Naguib
Journal:  Anesthesiology       Date:  2009-05       Impact factor: 7.892

Review 10.  Antagonism of non-depolarising neuromuscular block: current practice.

Authors:  A F Kopman; M Eikermann
Journal:  Anaesthesia       Date:  2009-03       Impact factor: 6.955

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  1 in total

1.  Pseudocholinesterase Deficiency Considerations: A Case Study.

Authors:  Bryant W Cornelius; Todd M Jacobs
Journal:  Anesth Prog       Date:  2020-09-01
  1 in total

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