Literature DB >> 29950713

First GPCR-directed antibody passes approval milestone.

Elie Dolgin.   

Abstract

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Year:  2018        PMID: 29950713     DOI: 10.1038/nrd.2018.103

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  12 in total

1.  Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors.

Authors:  Erica R Hendrikse; Lydia P Liew; Rebekah L Bower; Muriel Bonnet; Muhammad A Jamaluddin; Nicole Prodan; Keith D Richards; Christopher S Walker; Garry Pairaudeau; David M Smith; Roxana-Maria Rujan; Risha Sudra; Christopher A Reynolds; Jason M Booe; Augen A Pioszak; Jack U Flanagan; Michael P Hay; Debbie L Hay
Journal:  ACS Pharmacol Transl Sci       Date:  2020-03-12

Review 2.  Improving antibody drug development using bionanotechnology.

Authors:  Emily K Makowski; John S Schardt; Peter M Tessier
Journal:  Curr Opin Biotechnol       Date:  2021-12-07       Impact factor: 10.279

3.  Patient Reported Ease-of-Use with a Disposable Autoinjector in Individuals with Migraine.

Authors:  Jennifer Mead; Ryan Dammerman; Soeren Rasmussen
Journal:  Patient Prefer Adherence       Date:  2020-07-08       Impact factor: 2.711

4.  Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors.

Authors:  María E Terrón-Díaz; Sara J Wright; Melina A Agosto; Olivier Lichtarge; Theodore G Wensel
Journal:  J Biol Chem       Date:  2019-11-01       Impact factor: 5.157

5.  Development of an Antigen-Antibody Co-Display System for Detecting Interaction of G-Protein-Coupled Receptors and Single-Chain Variable Fragments.

Authors:  Yinjie Zhang; Boyang Jason Wu; Xiaolan Yu; Ping Luo; Hao Ye; Yan Yu; Wei Han; Jingjing Li
Journal:  Int J Mol Sci       Date:  2021-04-29       Impact factor: 5.923

6.  Structure-guided discovery of a single-domain antibody agonist against human apelin receptor.

Authors:  Yanbin Ma; Yao Ding; Xianqiang Song; Xiaochuan Ma; Xun Li; Ning Zhang; Yunpeng Song; Yaping Sun; Yuqing Shen; Wenge Zhong; Liaoyuan A Hu; Yingli Ma; Mei-Yun Zhang
Journal:  Sci Adv       Date:  2020-01-15       Impact factor: 14.136

Review 7.  Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy.

Authors:  Ramiro Vázquez; Maria E Riveiro; Caroline Berenguer-Daizé; Anthony O'Kane; Julie Gormley; Olivier Touzelet; Keyvan Rezai; Mohamed Bekradda; L'Houcine Ouafik
Journal:  Front Oncol       Date:  2021-01-06       Impact factor: 6.244

8.  Function-based high-throughput screening for antibody antagonists and agonists against G protein-coupled receptors.

Authors:  Huanhuan Ren; Jian Li; Ning Zhang; Liaoyuan A Hu; Yingli Ma; Philip Tagari; Jianqing Xu; Mei-Yun Zhang
Journal:  Commun Biol       Date:  2020-03-26

Review 9.  Antigen Design for Successful Isolation of Highly Challenging Therapeutic Anti-GPCR Antibodies.

Authors:  Man-Seok Ju; Sang Taek Jung
Journal:  Int J Mol Sci       Date:  2020-11-03       Impact factor: 5.923

10.  Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin.

Authors:  Sara Gómez-Melero; Fé Isabel García-Maceira; Tania García-Maceira; Verónica Luna-Guerrero; Gracia Montero-Peñalvo; Isaac Túnez-Fiñana; Elier Paz-Rojas
Journal:  BMC Biotechnol       Date:  2021-07-05       Impact factor: 2.563

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