Thainá Rodrigues Melo Santos1, Juliana Valeria Melo1, Nathalie Carvalho Leite2, Gil Fernando Salles2, Claudia Regina Lopes Cardoso3. 1. Department of Occupational Therapy, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Brazil. 2. Department of Internal Medicine, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Brazil. 3. Department of Internal Medicine, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Brazil. Electronic address: claudiacardoso@hucff.ufrj.br.
Abstract
AIMS: To investigate the associated factors with the vibration threshold perception (VPT) in patients with type 2 diabetes and to assess whether it is useful for detection of diabetic peripheral neuropathy (DPN). METHODS: VPTs were measured with Vibration Sensory Analyzer (VSA-3000) in 426 diabetic patients. The diagnosis of DPN was based on Neuropathy Symptom Score and Neuropathy Disability Score (NDS). ROC curve analysis and multiple linear and logistic regressions were performed to investigate the associations between VPT and DPN. RESULTS: Values of VPT were progressively higher according to NDS stages. Age, height, diabetes duration, and mean cumulative HbA1c exposure (partial correlation coefficients: 0.34; 0.27; 0.10; and 0.13; respectively) were the variables independently associated with VPT. Area under ROC curve of VPT for detection of DPN was 0.71 (95% CI: 0.66-0.75) and >8.9 μm was its best cut-off value. VPT, age, female sex, height, diabetes duration and mean HbA1c levels were the independent correlates of the presence of DPN. An increased VPT triplicate the likelihood of having DPN (OR: 3.24; 95% CI: 2.05-5.11). CONCLUSIONS: VPT, measured by an automatic device, shares common correlates with DPN and is strongly associated with its presence. VPT testing may be useful as a screening tool for DPN assessment. Published by Elsevier Inc.
AIMS: To investigate the associated factors with the vibration threshold perception (VPT) in patients with type 2 diabetes and to assess whether it is useful for detection of diabetic peripheral neuropathy (DPN). METHODS: VPTs were measured with Vibration Sensory Analyzer (VSA-3000) in 426 diabeticpatients. The diagnosis of DPN was based on Neuropathy Symptom Score and Neuropathy Disability Score (NDS). ROC curve analysis and multiple linear and logistic regressions were performed to investigate the associations between VPT and DPN. RESULTS: Values of VPT were progressively higher according to NDS stages. Age, height, diabetes duration, and mean cumulative HbA1c exposure (partial correlation coefficients: 0.34; 0.27; 0.10; and 0.13; respectively) were the variables independently associated with VPT. Area under ROC curve of VPT for detection of DPN was 0.71 (95% CI: 0.66-0.75) and >8.9 μm was its best cut-off value. VPT, age, female sex, height, diabetes duration and mean HbA1c levels were the independent correlates of the presence of DPN. An increased VPT triplicate the likelihood of having DPN (OR: 3.24; 95% CI: 2.05-5.11). CONCLUSIONS: VPT, measured by an automatic device, shares common correlates with DPN and is strongly associated with its presence. VPT testing may be useful as a screening tool for DPN assessment. Published by Elsevier Inc.
Authors: Jisang Jung; Min-Gyu Kim; Youn-Joo Kang; Kyungwan Min; Kyung-Ah Han; Hyoseon Choi Journal: Int J Environ Res Public Health Date: 2021-06-04 Impact factor: 3.390
Authors: Mozania Reis de Matos; Daniele Pereira Santos-Bezerra; Cristiane das Graças Dias Cavalcante; Jacira Xavier de Carvalho; Juliana Leite; Jose Antonio Januario Neves; Sharon Nina Admoni; Marisa Passarelli; Maria Candida Parisi; Maria Lucia Correa-Giannella Journal: Int J Environ Res Public Health Date: 2020-05-06 Impact factor: 3.390
Authors: Jamie Burgess; Bernhard Frank; Andrew Marshall; Rashaad S Khalil; Georgios Ponirakis; Ioannis N Petropoulos; Daniel J Cuthbertson; Rayaz A Malik; Uazman Alam Journal: Diagnostics (Basel) Date: 2021-01-24