PURPOSE: The aim of our study is to determine if there is a natural progression of QRSd in ICD-only patients. METHODS AND RESULTS: Retrospective study over a 7-year period of 86 consecutive patients who underwent ICD-only implantation in 2008 at the Liverpool Heart and Chest Hospital, UK. The mean age at ICD implantation was 62.3 (± 11.5) years, range 24-82 years. Mean length of follow-up ECGs available was 5.0 (± 1.6) years, total of 431 patient-years. We observed a progressive prolongation of QRSd over the 7-year study period. The linear mixed model found a statistically significant (p < 0.001) increase in QRSd over time, as measured in years. Clinically important progression of QRSd to ≥ 120 ms was observed in 30% of patients after 2.7 (± 1.5) years and progression of QRSd to ≥ 150 ms was observed in 10% of patients after 2.9 (± 1.2) years. CONCLUSIONS: The natural progression of QRS duration in ICD patients may have serious implications for device implantation. Our study found that the QRS duration increased at a rate of 3.1 ms per year in ICD patients.
PURPOSE: The aim of our study is to determine if there is a natural progression of QRSd in ICD-onlypatients. METHODS AND RESULTS: Retrospective study over a 7-year period of 86 consecutive patients who underwent ICD-only implantation in 2008 at the Liverpool Heart and Chest Hospital, UK. The mean age at ICD implantation was 62.3 (± 11.5) years, range 24-82 years. Mean length of follow-up ECGs available was 5.0 (± 1.6) years, total of 431 patient-years. We observed a progressive prolongation of QRSd over the 7-year study period. The linear mixed model found a statistically significant (p < 0.001) increase in QRSd over time, as measured in years. Clinically important progression of QRSd to ≥ 120 ms was observed in 30% of patients after 2.7 (± 1.5) years and progression of QRSd to ≥ 150 ms was observed in 10% of patients after 2.9 (± 1.2) years. CONCLUSIONS: The natural progression of QRS duration in ICDpatients may have serious implications for device implantation. Our study found that the QRS duration increased at a rate of 3.1 ms per year in ICDpatients.
Authors: Anthony S L Tang; George A Wells; Mario Talajic; Malcolm O Arnold; Robert Sheldon; Stuart Connolly; Stefan H Hohnloser; Graham Nichol; David H Birnie; John L Sapp; Raymond Yee; Jeffrey S Healey; Jean L Rouleau Journal: N Engl J Med Date: 2010-11-14 Impact factor: 91.245
Authors: Michele Brignole; Angelo Auricchio; Gonzalo Baron-Esquivias; Pierre Bordachar; Giuseppe Boriani; Ole-A Breithardt; John Cleland; Jean-Claude Deharo; Victoria Delgado; Perry M Elliott; Bulent Gorenek; Carsten W Israel; Christophe Leclercq; Cecilia Linde; Lluís Mont; Luigi Padeletti; Richard Sutton; Panos E Vardas; Jose Luis Zamorano; Stephan Achenbach; Helmut Baumgartner; Jeroen J Bax; Héctor Bueno; Veronica Dean; Christi Deaton; Cetin Erol; Robert Fagard; Roberto Ferrari; David Hasdai; Arno W Hoes; Paulus Kirchhof; Juhani Knuuti; Philippe Kolh; Patrizio Lancellotti; Ales Linhart; Petros Nihoyannopoulos; Massimo F Piepoli; Piotr Ponikowski; Per Anton Sirnes; Juan Luis Tamargo; Michal Tendera; Adam Torbicki; William Wijns; Stephan Windecker; Paulus Kirchhof; Carina Blomstrom-Lundqvist; Luigi P Badano; Farid Aliyev; Dietmar Bänsch; Helmut Baumgartner; Walid Bsata; Peter Buser; Philippe Charron; Jean-Claude Daubert; Dan Dobreanu; Svein Faerestrand; David Hasdai; Arno W Hoes; Jean-Yves Le Heuzey; Hercules Mavrakis; Theresa McDonagh; Jose Luis Merino; Mostapha M Nawar; Jens Cosedis Nielsen; Burkert Pieske; Lidija Poposka; Frank Ruschitzka; Michal Tendera; Isabelle C Van Gelder; Carol M Wilson Journal: Eur Heart J Date: 2013-06-24 Impact factor: 29.983
Authors: Piotr Ponikowski; Adriaan A Voors; Stefan D Anker; Héctor Bueno; John G F Cleland; Andrew J S Coats; Volkmar Falk; José Ramón González-Juanatey; Veli-Pekka Harjola; Ewa A Jankowska; Mariell Jessup; Cecilia Linde; Petros Nihoyannopoulos; John T Parissis; Burkert Pieske; Jillian P Riley; Giuseppe M C Rosano; Luis M Ruilope; Frank Ruschitzka; Frans H Rutten; Peter van der Meer Journal: Eur J Heart Fail Date: 2016-05-20 Impact factor: 15.534
Authors: Arnold J Greenspon; Jasmine D Patel; Edmund Lau; Jorge A Ochoa; Daniel R Frisch; Reginald T Ho; Behzad B Pavri; Steven M Kurtz Journal: J Am Coll Cardiol Date: 2012-09-19 Impact factor: 24.094
Authors: Cecilia Linde; William T Abraham; Michael R Gold; Martin St John Sutton; Stefano Ghio; Claude Daubert Journal: J Am Coll Cardiol Date: 2008-11-07 Impact factor: 24.094
Authors: Arthur J Moss; W Jackson Hall; David S Cannom; Helmut Klein; Mary W Brown; James P Daubert; N A Mark Estes; Elyse Foster; Henry Greenberg; Steven L Higgins; Marc A Pfeffer; Scott D Solomon; David Wilber; Wojciech Zareba Journal: N Engl J Med Date: 2009-09-01 Impact factor: 91.245