| Literature DB >> 2994589 |
Abstract
The ability of cAMP to inhibit isoleucyl-tRNA synthetase (IRS) formation has been demonstrated in wild type K-12 Escherichia coli and two adenyl-cyclase (cya) mutants. cAMP appeared not to have any effect on either the valyl- or arginyl-tRNA synthetase (VRS and ARS respectively). Addition of cAMP led to a reduction in rate of IRS synthesis but not VRS or ARS. Furthermore, derepression of IRS and VRS by isoleucine limitation was completely prevented by cAMP.Entities:
Mesh:
Substances:
Year: 1985 PMID: 2994589 DOI: 10.1007/bf00447066
Source DB: PubMed Journal: Arch Microbiol ISSN: 0302-8933 Impact factor: 2.552