Literature DB >> 29945725

The Increasingly Human and Profitable Monoclonal Antibody Market.

António L Grilo1, A Mantalaris2.   

Abstract

The monoclonal antibody (mAb) market has changed rapidly in the past 5 years: it has doubled in size, becoming dominated by fully human molecules, launched bispecific molecules, and faced competition from biosimilars. We summarize the market in terms of therapeutic applications, type and structure of mAbs, dominant companies, manufacturing locations, and emerging markets.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  biosimilars; market analysis; monoclonal antibody

Mesh:

Substances:

Year:  2018        PMID: 29945725     DOI: 10.1016/j.tibtech.2018.05.014

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  92 in total

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2.  Primary Human Natural Killer Cells Retain Proinflammatory IgG1 at the Cell Surface and Express CD16a Glycoforms with Donor-dependent Variability.

Authors:  Kashyap R Patel; Joel D Nott; Adam W Barb
Journal:  Mol Cell Proteomics       Date:  2019-08-29       Impact factor: 5.911

3.  Rapid, quantitative determination of aggregation and particle formation for antibody drug conjugate therapeutics with label-free Raman spectroscopy.

Authors:  Chi Zhang; Jeremy S Springall; Xiangyang Wang; Ishan Barman
Journal:  Anal Chim Acta       Date:  2019-07-10       Impact factor: 6.558

4.  Correlation between antidrug antibodies, pre-existing antidrug reactivity, and immunogenetics (MHC class II alleles) in cynomolgus macaque.

Authors:  Natalia Kovalova; Michael D Knierman; Patricia L Brown-Augsburger; Victor J Wroblewski; Lukasz K Chlewicki
Journal:  Immunogenetics       Date:  2019-11-27       Impact factor: 2.846

5.  Structure and development of single domain antibodies as modules for therapeutics and diagnostics.

Authors:  Robert J Hoey; Hyeyoung Eom; James R Horn
Journal:  Exp Biol Med (Maywood)       Date:  2019-10-09

6.  Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and Its Biological Applications.

Authors:  Wei Tao; Junqing Wang; Wolfgang J Parak; Omid C Farokhzad; Jinjun Shi
Journal:  ACS Nano       Date:  2019-04-15       Impact factor: 15.881

7.  Systematic Activity Maturation of a Single-Domain Antibody with Non-canonical Amino Acids through Chemical Mutagenesis.

Authors:  Philip R Lindstedt; Francesco A Aprile; Pietro Sormanni; Robertinah Rakoto; Christopher M Dobson; Gonçalo J L Bernardes; Michele Vendruscolo
Journal:  Cell Chem Biol       Date:  2020-11-19       Impact factor: 8.116

8.  Multiscale engineering of immune cells and lymphoid organs.

Authors:  Sungwoong Kim; Shivem B Shah; Pamela L Graney; Ankur Singh
Journal:  Nat Rev Mater       Date:  2019-04-03       Impact factor: 66.308

Review 9.  Therapies for rare diseases: therapeutic modalities, progress and challenges ahead.

Authors:  Erik Tambuyzer; Benjamin Vandendriessche; Christopher P Austin; Philip J Brooks; Kristina Larsson; Katherine I Miller Needleman; James Valentine; Kay Davies; Stephen C Groft; Robert Preti; Tudor I Oprea; Marco Prunotto
Journal:  Nat Rev Drug Discov       Date:  2019-12-13       Impact factor: 84.694

10.  Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.

Authors:  Kristina Srzentić; Luca Fornelli; Yury O Tsybin; Joseph A Loo; Henrique Seckler; Jeffrey N Agar; Lissa C Anderson; Dina L Bai; Alain Beck; Jennifer S Brodbelt; Yuri E M van der Burgt; Julia Chamot-Rooke; Sneha Chatterjee; Yunqiu Chen; David J Clarke; Paul O Danis; Jolene K Diedrich; Robert A D'Ippolito; Mathieu Dupré; Natalia Gasilova; Ying Ge; Young Ah Goo; David R Goodlett; Sylvester Greer; Kim F Haselmann; Lidong He; Christopher L Hendrickson; Joshua D Hinkle; Matthew V Holt; Sam Hughes; Donald F Hunt; Neil L Kelleher; Anton N Kozhinov; Ziqing Lin; Christian Malosse; Alan G Marshall; Laure Menin; Robert J Millikin; Konstantin O Nagornov; Simone Nicolardi; Ljiljana Paša-Tolić; Stuart Pengelley; Neil R Quebbemann; Anja Resemann; Wendy Sandoval; Richa Sarin; Nicholas D Schmitt; Jeffrey Shabanowitz; Jared B Shaw; Michael R Shortreed; Lloyd M Smith; Frank Sobott; Detlev Suckau; Timothy Toby; Chad R Weisbrod; Norelle C Wildburger; John R Yates; Sung Hwan Yoon; Nicolas L Young; Mowei Zhou
Journal:  J Am Soc Mass Spectrom       Date:  2020-08-19       Impact factor: 3.109

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