Literature DB >> 29944481

Treatment of Kratom Dependence With Buprenorphine-Naloxone Maintenance.

Megan Buresh1.   

Abstract

INTRODUCTION: Use of the unregulated herbal supplement kratom is on the rise in the United States. We present a case series of 2 patients who developed kratom dependence and withdrawal who were successfully transitioned to buprenorphine-naloxone maintenance. CASE
SUMMARY: Two patients using kratom to self-treat chronic pain after prescription opioids were discontinued presenting to our clinic with evidence of kratom dependence and withdrawal. On examination, both patients showed signs of mild opioid withdrawal. Both patients were successfully transitioned to buprenorphine-naloxone maintenance via home initiation with control of both their opioid withdrawal and chronic pain.
CONCLUSIONS: Kratom use is on the rise and with increasing evidence of developing opioid-type dependence due to chronic kratom use. This case series shows that buprenorphine can be used to treat kratom dependence and underlying chronic pain that drives it use.

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Year:  2018        PMID: 29944481     DOI: 10.1097/ADM.0000000000000428

Source DB:  PubMed          Journal:  J Addict Med        ISSN: 1932-0620            Impact factor:   3.702


  8 in total

1.  The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids.

Authors:  Laura Flores-Bocanegra; Huzefa A Raja; Tyler N Graf; Mario Augustinović; E Diane Wallace; Shabnam Hematian; Joshua J Kellogg; Daniel A Todd; Nadja B Cech; Nicholas H Oberlies
Journal:  J Nat Prod       Date:  2020-06-29       Impact factor: 4.050

2.  Cardiac arrest in a young healthy male patient secondary to kratom ingestion: is this 'legal high' substance more dangerous than initially thought ?

Authors:  Hafez Mohammad Ammar Abdullah; Iqra Haq; Randall Lamfers
Journal:  BMJ Case Rep       Date:  2019-07-19

3.  Associations of Lifetime Nonmedical Opioid, Methamphetamine, and Kratom Use within a Nationally Representative US Sample.

Authors:  Kirsten E Smith; Jeffrey M Rogers; Justin C Strickland
Journal:  J Psychoactive Drugs       Date:  2021-11-29

Review 4.  Health Effects Associated With Kratom (Mitragyna speciosa) and Polysubstance Use: A Narrative Review.

Authors:  Catherine W Striley; Carolin C Hoeflich; Andrew T Viegas; Lindsey A Berkowitz; Emily G Matthews; Leyla P Akin; Chidinma Iheanyi-Okeahialam; Urmeen Mansoor; Christopher R McCurdy
Journal:  Subst Abuse       Date:  2022-05-20

5.  A Case of Kratom-induced Seizures.

Authors:  Hasnain Afzal; Michael Esang; Sabreen Rahman
Journal:  Cureus       Date:  2020-01-07

6.  Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant.

Authors:  Alessandro E Vento; Simone de Persis; Sergio De Filippis; Fabrizio Schifano; Flavia Napoletano; John M Corkery; Georgios D Kotzalidis
Journal:  Front Psychiatry       Date:  2021-03-31       Impact factor: 4.157

7.  Complicated postoperative course secondary to kratom withdrawal: a case report.

Authors:  Michael Kucharik; Anupam Gupta; Peter Averkiou; George R Luck; Andrew S Ross
Journal:  J Surg Case Rep       Date:  2019-11-05

8.  Methadone, Buprenorphine, and Clonidine Attenuate Mitragynine Withdrawal in Rats.

Authors:  Rahimah Hassan; Sasidharan Sreenivasan; Christian P Müller; Zurina Hassan
Journal:  Front Pharmacol       Date:  2021-07-12       Impact factor: 5.810

  8 in total

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