Literature DB >> 29943816

The Role of Quantitative Systems Pharmacology in the Design of First-in-Human Trials.

Piet H van der Graaf1,2, Neil Benson2.   

Abstract

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Year:  2018        PMID： 29943816     DOI： 10.1002/cpt.1145

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


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  7 in total

1.  Quantitative systems pharmacology analysis of drug combination and scaling to humans: the interaction between noradrenaline and vasopressin in vasoconstriction.

Authors:  Anyue Yin; Akihiro Yamada; Wiro B Stam; Johan G C van Hasselt; Piet H van der Graaf
Journal:  Br J Pharmacol       Date:  2018-07-10       Impact factor: 8.739

Review 2.  Translational Quantitative Systems Pharmacology in Drug Development: from Current Landscape to Good Practices.

Authors:  Jane P F Bai; Justin C Earp; Venkateswaran C Pillai
Journal:  AAPS J       Date:  2019-06-03       Impact factor: 4.009

3.  Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy.

Authors:  Krina Mehta; Tingjie Guo; Robert S Wallis; Piet H van der Graaf; J G Coen van Hasselt
Journal:  Antimicrob Agents Chemother       Date:  2022-07-14       Impact factor: 5.938

Review 4.  Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology.

Authors:  Alison Betts; Piet H van der Graaf
Journal:  Clin Pharmacol Ther       Date:  2020-07-20       Impact factor: 6.875

5.  Evaluation framework for systems models.

Authors:  Sietse Braakman; Pras Pathmanathan; Helen Moore
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2022-01-10

6.  Current practices for QSP model assessment: an IQ consortium survey.

Authors:  Jason R Chan; Richard Allen; Britton Boras; Antonio Cabal; Valeriu Damian; Francis D Gibbons; Abhishek Gulati; Iraj Hosseini; Jeffrey D Kearns; Ryuta Saito; Lourdes Cucurull-Sanchez; Jangir Selimkhanov; Andrew M Stein; Kenichi Umehara; Guanyu Wang; Weirong Wang; Susana Neves-Zaph
Journal:  J Pharmacokinet Pharmacodyn       Date:  2022-08-11       Impact factor: 2.410

7.  Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.

Authors:  Kumpal Madrasi; Raibatak Das; Hafiz Mohmmadabdul; Lin Lin; Bradley T Hyman; Douglas A Lauffenburger; Mark W Albers; Robert A Rissman; John M Burke; Joshua F Apgar; Lucia Wille; Lore Gruenbaum; Fei Hua
Journal:  Alzheimers Dement       Date:  2021-05-02       Impact factor: 21.566
  7 in total

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