Literature DB >> 29941899

Lessons for cancer drug treatment from tackling a non-cancerous overgrowth syndrome.

Robert K Semple, Bart Vanhaesebroeck.   

Abstract

Entities:  

Keywords:  Cancer; Medical research

Mesh：

Substances：

Year:  2018        PMID： 29941899     DOI： 10.1038/d41586-018-05365-w

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  13 in total

1.  High frequency of mutations of the PIK3CA gene in human cancers.

Authors:  Yardena Samuels; Zhenghe Wang; Alberto Bardelli; Natalie Silliman; Janine Ptak; Steve Szabo; Hai Yan; Adi Gazdar; Steven M Powell; Gregory J Riggins; James K V Willson; Sanford Markowitz; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
Journal:  Science       Date:  2004-03-11       Impact factor: 47.728

2.  An estimation of the number of cells in the human body.

Authors:  Eva Bianconi; Allison Piovesan; Federica Facchin; Alina Beraudi; Raffaella Casadei; Flavia Frabetti; Lorenza Vitale; Maria Chiara Pelleri; Simone Tassani; Francesco Piva; Soledad Perez-Amodio; Pierluigi Strippoli; Silvia Canaider
Journal:  Ann Hum Biol       Date:  2013-07-05       Impact factor: 1.533

Review 3.  65 YEARS OF THE DOUBLE HELIX: One gene, many endocrine and metabolic syndromes: PTEN-opathies and precision medicine.

Authors:  Lamis Yehia; Charis Eng
Journal:  Endocr Relat Cancer       Date:  2018-05-23       Impact factor: 5.678

4.  Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome.

Authors:  Kyle C Kurek; Valerie L Luks; Ugur M Ayturk; Ahmad I Alomari; Steven J Fishman; Samantha A Spencer; John B Mulliken; Margot E Bowen; Guilherme L Yamamoto; Harry P W Kozakewich; Matthew L Warman
Journal:  Am J Hum Genet       Date:  2012-05-31       Impact factor: 11.025

Review 5.  Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance.

Authors:  Enrique Rozengurt; Heloisa P Soares; James Sinnet-Smith
Journal:  Mol Cancer Ther       Date:  2014-10-16       Impact factor: 6.261

6.  Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

Authors:  Quitterie Venot; Thomas Blanc; Smail Hadj Rabia; Laureline Berteloot; Sophia Ladraa; Jean-Paul Duong; Estelle Blanc; Simon C Johnson; Clément Hoguin; Olivia Boccara; Sabine Sarnacki; Nathalie Boddaert; Stephanie Pannier; Frank Martinez; Sato Magassa; Junna Yamaguchi; Bertrand Knebelmann; Pierre Merville; Nicolas Grenier; Dominique Joly; Valérie Cormier-Daire; Caroline Michot; Christine Bole-Feysot; Arnaud Picard; Véronique Soupre; Stanislas Lyonnet; Jeremy Sadoine; Lotfi Slimani; Catherine Chaussain; Cécile Laroche-Raynaud; Laurent Guibaud; Christine Broissand; Jeanne Amiel; Christophe Legendre; Fabiola Terzi; Guillaume Canaud
Journal:  Nature       Date:  2018-06-13       Impact factor: 49.962

7.  Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA.

Authors:  Marjorie J Lindhurst; Victoria E R Parker; Felicity Payne; Julie C Sapp; Simon Rudge; Julie Harris; Alison M Witkowski; Qifeng Zhang; Matthijs P Groeneveld; Carol E Scott; Allan Daly; Susan M Huson; Laura L Tosi; Michael L Cunningham; Thomas N Darling; Joseph Geer; Zoran Gucev; V Reid Sutton; Christos Tziotzios; Adrian K Dixon; Timothy Helliwell; Stephen O'Rahilly; David B Savage; Michael J O Wakelam; Inês Barroso; Leslie G Biesecker; Robert K Semple
Journal:  Nat Genet       Date:  2012-06-24       Impact factor: 38.330

8.  Tracking the Evolution of Non-Small-Cell Lung Cancer.

Authors:  Mariam Jamal-Hanjani; Gareth A Wilson; Nicholas McGranahan; Nicolai J Birkbak; Thomas B K Watkins; Selvaraju Veeriah; Seema Shafi; Diana H Johnson; Richard Mitter; Rachel Rosenthal; Max Salm; Stuart Horswell; Mickael Escudero; Nik Matthews; Andrew Rowan; Tim Chambers; David A Moore; Samra Turajlic; Hang Xu; Siow-Ming Lee; Martin D Forster; Tanya Ahmad; Crispin T Hiley; Christopher Abbosh; Mary Falzon; Elaine Borg; Teresa Marafioti; David Lawrence; Martin Hayward; Shyam Kolvekar; Nikolaos Panagiotopoulos; Sam M Janes; Ricky Thakrar; Asia Ahmed; Fiona Blackhall; Yvonne Summers; Rajesh Shah; Leena Joseph; Anne M Quinn; Phil A Crosbie; Babu Naidu; Gary Middleton; Gerald Langman; Simon Trotter; Marianne Nicolson; Hardy Remmen; Keith Kerr; Mahendran Chetty; Lesley Gomersall; Dean A Fennell; Apostolos Nakas; Sridhar Rathinam; Girija Anand; Sajid Khan; Peter Russell; Veni Ezhil; Babikir Ismail; Melanie Irvin-Sellers; Vineet Prakash; Jason F Lester; Malgorzata Kornaszewska; Richard Attanoos; Haydn Adams; Helen Davies; Stefan Dentro; Philippe Taniere; Brendan O'Sullivan; Helen L Lowe; John A Hartley; Natasha Iles; Harriet Bell; Yenting Ngai; Jacqui A Shaw; Javier Herrero; Zoltan Szallasi; Roland F Schwarz; Aengus Stewart; Sergio A Quezada; John Le Quesne; Peter Van Loo; Caroline Dive; Allan Hackshaw; Charles Swanton
Journal:  N Engl J Med       Date:  2017-04-26       Impact factor: 91.245

9.  De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes.

Authors:  Jean-Baptiste Rivière; Ghayda M Mirzaa; Brian J O'Roak; Margaret Beddaoui; Diana Alcantara; Robert L Conway; Judith St-Onge; Jeremy A Schwartzentruber; Karen W Gripp; Sarah M Nikkel; Thea Worthylake; Christopher T Sullivan; Thomas R Ward; Hailly E Butler; Nancy A Kramer; Beate Albrecht; Christine M Armour; Linlea Armstrong; Oana Caluseriu; Cheryl Cytrynbaum; Beth A Drolet; A Micheil Innes; Julie L Lauzon; Angela E Lin; Grazia M S Mancini; Wendy S Meschino; James D Reggin; Anand K Saggar; Tally Lerman-Sagie; Gökhan Uyanik; Rosanna Weksberg; Birgit Zirn; Chandree L Beaulieu; Jacek Majewski; Dennis E Bulman; Mark O'Driscoll; Jay Shendure; John M Graham; Kym M Boycott; William B Dobyns
Journal:  Nat Genet       Date:  2012-06-24       Impact factor: 38.330

10.  Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.

Authors:  Sandra D Castillo; Elena Tzouanacou; May Zaw-Thin; Inma M Berenjeno; Victoria E R Parker; Iñigo Chivite; Maria Milà-Guasch; Wayne Pearce; Isabelle Solomon; Ana Angulo-Urarte; Ana M Figueiredo; Robert E Dewhurst; Rachel G Knox; Graeme R Clark; Cheryl L Scudamore; Adam Badar; Tammy L Kalber; Julie Foster; Daniel J Stuckey; Anna L David; Wayne A Phillips; Mark F Lythgoe; Valerie Wilson; Robert K Semple; Neil J Sebire; Veronica A Kinsler; Mariona Graupera; Bart Vanhaesebroeck
Journal:  Sci Transl Med       Date:  2016-03-30       Impact factor: 17.956
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  3 in total

Review 1.  Cancer-Associated PIK3CA Mutations in Overgrowth Disorders.

Authors:  Ralitsa R Madsen; Bart Vanhaesebroeck; Robert K Semple
Journal:  Trends Mol Med       Date:  2018-09-06       Impact factor: 11.951

Review 2.  PIK3CA Gene Mutations in Solid Malignancies: Association with Clinicopathological Parameters and Prognosis.

Authors:  Ali Alqahtani; Hazem S K Ayesh; Hafez Halawani
Journal:  Cancers (Basel)       Date:  2019-12-30       Impact factor: 6.639

Review 3.  Perspective: Potential Impact and Therapeutic Implications of Oncogenic PI3K Activation on Chromosomal Instability.

Authors:  Bart Vanhaesebroeck; Benoit Bilanges; Ralitsa R Madsen; Katie L Dale; Evelyn Lau; Elina Vladimirou
Journal:  Biomolecules       Date:  2019-08-01
  3 in total

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