Literature DB >> 15016963

High frequency of mutations of the PIK3CA gene in human cancers.

Yardena Samuels1, Zhenghe Wang, Alberto Bardelli, Natalie Silliman, Janine Ptak, Steve Szabo, Hai Yan, Adi Gazdar, Steven M Powell, Gregory J Riggins, James K V Willson, Sanford Markowitz, Kenneth W Kinzler, Bert Vogelstein, Victor E Velculescu.   

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Year:  2004        PMID: 15016963     DOI: 10.1126/science.1096502

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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  1351 in total

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5.  Molecular mechanism of activation of class IA phosphoinositide 3-kinases (PI3Ks) by membrane-localized HRas.

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Authors:  John P Gustin; David P Cosgrove; Ben Ho Park
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