Atilla Yilmaz1, Elif Tuğba Sarac2, Fatma Esen Aydinli3, Mustafa Turgut Yildizgoren4, Emine Esra Okuyucu5, Yurdal Serarslan6. 1. Department of Neurosurgery, Faculty of Medicine, Mustafa Kemal University, Anatakya, Hatay, Turkey. atillayilmaz@hotmail.com. 2. Department of Otorhinolaryngology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey. 3. Department of Speech and Language Therapy, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey. 4. Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey. 5. Department of Neurology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey. 6. Department of Neurosurgery, Faculty of Medicine, Mustafa Kemal University, Anatakya, Hatay, Turkey.
Abstract
INTRODUCTION: Parkinson's disease (PD) is the second most frequent progressive neuro-degenerative disorder. In addition to motor symptoms, nonmotor symptoms and voice and speech disorders can also develop in 90% of PD patients. The aim of our study was to investigate the effects of DBS and different DBS frequencies on speech acoustics of vowels in PD patients. METHODS: The study included 16 patients who underwent STN-DBS surgery due to PD. The voice recordings for the vowels including [a], [e], [i], and [o] were performed at frequencies including 230, 130, 90, and 60 Hz and off-stimulation. The voice recordings were gathered and evaluated by the Praat software, and the effects on the first (F1), second (F2), and third formant (F3) frequencies were analyzed. RESULTS: A significant difference was found for the F1 value of the vowel [a] at 130 Hz compared to off-stimulation. However, no significant difference was found between the three formant frequencies with regard to the stimulation frequencies and off-stimulation. In addition, though not statistically significant, stimulation at 60 and 230 Hz led to several differences in the formant frequencies of other three vowels. CONCLUSION: Our results indicated that STN-DBS stimulation at 130 Hz had a significant positive effect on articulation of [a] compared to off-stimulation. Although there is not any statistical significant stimulation at 60 and 230 Hz may also have an effect on the articulation of [e], [i], and [o] but this effect needs to be investigated in future studies with higher numbers of participants.
INTRODUCTION:Parkinson's disease (PD) is the second most frequent progressive neuro-degenerative disorder. In addition to motor symptoms, nonmotor symptoms and voice and speech disorders can also develop in 90% of PDpatients. The aim of our study was to investigate the effects of DBS and different DBS frequencies on speech acoustics of vowels in PDpatients. METHODS: The study included 16 patients who underwent STN-DBS surgery due to PD. The voice recordings for the vowels including [a], [e], [i], and [o] were performed at frequencies including 230, 130, 90, and 60 Hz and off-stimulation. The voice recordings were gathered and evaluated by the Praat software, and the effects on the first (F1), second (F2), and third formant (F3) frequencies were analyzed. RESULTS: A significant difference was found for the F1 value of the vowel [a] at 130 Hz compared to off-stimulation. However, no significant difference was found between the three formant frequencies with regard to the stimulation frequencies and off-stimulation. In addition, though not statistically significant, stimulation at 60 and 230 Hz led to several differences in the formant frequencies of other three vowels. CONCLUSION: Our results indicated that STN-DBS stimulation at 130 Hz had a significant positive effect on articulation of [a] compared to off-stimulation. Although there is not any statistical significant stimulation at 60 and 230 Hz may also have an effect on the articulation of [e], [i], and [o] but this effect needs to be investigated in future studies with higher numbers of participants.
Authors: J Gamboa; F J Jiménez-Jiménez; A Nieto; J Montojo; M Ortí-Pareja; J A Molina; E García-Albea; I Cobeta Journal: J Voice Date: 1997-09 Impact factor: 2.009
Authors: Jeff M Bronstein; Michele Tagliati; Ron L Alterman; Andres M Lozano; Jens Volkmann; Alessandro Stefani; Fay B Horak; Michael S Okun; Kelly D Foote; Paul Krack; Rajesh Pahwa; Jaimie M Henderson; Marwan I Hariz; Roy A Bakay; Ali Rezai; William J Marks; Elena Moro; Jerrold L Vitek; Frances M Weaver; Robert E Gross; Mahlon R DeLong Journal: Arch Neurol Date: 2010-10-11