Literature DB >> 2993471

High affinity binding of 125I-labeled human tumor necrosis factor (LuKII) to specific cell surface receptors.

B Y Rubin, S L Anderson, S A Sullivan, B D Williamson, E A Carswell, L J Old.   

Abstract

125I-labeled TNF(LuKII) (tumor necrosis factor) binds specifically to human and mouse cell lines sensitive to the cytotoxic effect of TNF, but not to cells made resistant to TNF. TNF-sensitive cells have cell surface receptors with a high affinity for TNF(LuKII). Mouse TNF competes with TNF(LuKII) for receptor binding. Scatchard analysis of the binding data yielded linear plots and suggests that TNF(LuKII) binds to homogeneous receptor sites. The number of TNF(LuKII) receptors on two TNF-sensitive cell lines is 200-300 per cell and the affinity constant of the receptor for TNF(LuKII) is approximately 1 X 10(-10) M.

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Year:  1985        PMID： 2993471      PMCID： PMC2187809          DOI： 10.1084/jem.162.3.1099

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  11 in total

1.  The human LT system. I. Physical-chemical heterogeneity of LT molecules released by mitogen activated human lymphocytes in vitro.

Authors:  G A Granger; R S Yamamoto; D S Fair; J C Hiserodt
Journal:  Cell Immunol       Date:  1978-07       Impact factor: 4.868

2.  Corynebacterium parvum as the priming agent in the production of tumor necrosis factor in the mouse.

Authors:  S Green; A Dobrjansky; M A Chiasson; E Carswell; M K Schwartz; L J Old
Journal:  J Natl Cancer Inst       Date:  1977-11       Impact factor: 13.506

3.  An endotoxin-induced serum factor that causes necrosis of tumors.

Authors:  E A Carswell; L J Old; R L Kassel; S Green; N Fiore; B Williamson
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

4.  High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor.

Authors:  M Aguet
Journal:  Nature       Date:  1980-04-03       Impact factor: 49.962

5.  Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin.

Authors:  D Pennica; G E Nedwin; J S Hayflick; P H Seeburg; R Derynck; M A Palladino; W J Kohr; B B Aggarwal; D V Goeddel
Journal:  Nature       Date:  1984 Dec 20-1985 Jan 2       Impact factor: 49.962

6.  Molecular cloning of the complementary DNA for human tumor necrosis factor.

Authors:  A M Wang; A A Creasey; M B Ladner; L S Lin; J Strickler; J N Van Arsdell; R Yamamoto; D F Mark
Journal:  Science       Date:  1985-04-12       Impact factor: 47.728

7.  Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon.

Authors:  B D Williamson; E A Carswell; B Y Rubin; J S Prendergast; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

8.  Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity.

Authors:  P W Gray; B B Aggarwal; C V Benton; T S Bringman; W J Henzel; J A Jarrett; D W Leung; B Moffat; P Ng; L P Svedersky
Journal:  Nature       Date:  1984 Dec 20-1985 Jan 2       Impact factor: 49.962

9.  Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor.

Authors:  T Shirai; H Yamaguchi; H Ito; C W Todd; R B Wallace
Journal:  Nature       Date:  1985 Feb 28-Mar 6       Impact factor: 49.962

10.  Cytotoxic activity of tumor necrosis factor (TNF) on human cancer cells in vitro.

Authors:  K Haranaka; N Satomi
Journal:  Jpn J Exp Med       Date:  1981-06
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  28 in total

1.  Antibodies against amino acids 1-15 of tumor necrosis factor block its binding to cell-surface receptor.

Authors:  S H Socher; M W Riemen; D Martinez; A Friedman; J Tai; J C Quintero; V Garsky; A Oliff
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

2.  Tumor necrosis factor inhibits MYC expression in HL-60 cells at the level of mRNA transcription.

Authors:  M Krönke; C Schlüter; K Pfizenmaier
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

3.  Tumour necrosis factor, cholestatic jaundice, and chronic liver disease.

Authors:  A Jones; P J Selby; C Viner; S Hobbs; M E Gore; T J McElwain
Journal:  Gut       Date:  1990-08       Impact factor: 23.059

4.  Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor.

Authors:  C Peetre; U Gullberg; E Nilsson; I Olsson
Journal:  J Clin Invest       Date:  1986-12       Impact factor: 14.808

5.  Regulation of human lung fibroblast glycosaminoglycan production by recombinant interferons, tumor necrosis factor, and lymphotoxin.

Authors:  J A Elias; R C Krol; B Freundlich; P M Sampson
Journal:  J Clin Invest       Date:  1988-02       Impact factor: 14.808

6.  Macrophage/monocyte receptor for nonenzymatically glycosylated protein is upregulated by cachectin/tumor necrosis factor.

Authors:  H Vlassara; L Moldawer; B Chan
Journal:  J Clin Invest       Date:  1989-12       Impact factor: 14.808

7.  Human tumor necrosis factor increases the resistance against Listeria infection in mice.

Authors:  K Kato; A Nakane; T Minagawa; N Kasai; K Yamamoto; N Sato; N Tsuruoka
Journal:  Med Microbiol Immunol       Date:  1989       Impact factor: 3.402

8.  Eradication of metastatic tumour cells from lymph nodes by local administration of anti-CD3 antibody.

Authors:  Y Dohi; S Sunada; M Aoki; A Moriguchi; M Okabayashi; M Miyata; H Matsuda
Journal:  Cancer Immunol Immunother       Date:  1993-06       Impact factor: 6.968

9.  Low-affinity receptors for tumour necrosis factor-alpha, interferon-gamma and granulocyte-macrophage colony-stimulating factor are expressed on human placental syncytiotrophoblast.

Authors:  J Hampson; P J McLaughlin; P M Johnson
Journal:  Immunology       Date:  1993-07       Impact factor: 7.397

10.  Purification, characterization, and antitumor activity of nonrecombinant mouse tumor necrosis factor.

Authors:  K Haranaka; E A Carswell; B D Williamson; J S Prendergast; N Satomi; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205
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