Literature DB >> 29934617

Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.

Wei-Feng Cai1, Cixiong Zhang1, Yu-Qing Wu1, Gui Zhuang1, Zhiyun Ye1, Chen-Song Zhang2, Sheng-Cai Lin3.   

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Year:  2018        PMID： 29934617      PMCID： PMC6082853          DOI： 10.1038/s41422-018-0057-z

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


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  15 in total

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Review 3.  Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine.

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4.  Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.

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5.  The B55α subunit of PP2A drives a p53-dependent metabolic adaptation to glutamine deprivation.

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6.  c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.

Authors:  Ping Gao; Irina Tchernyshyov; Tsung-Cheng Chang; Yun-Sil Lee; Kayoko Kita; Takafumi Ochi; Karen I Zeller; Angelo M De Marzo; Jennifer E Van Eyk; Joshua T Mendell; Chi V Dang
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8.  Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.

Authors:  Daniela Gaglio; Chiara Soldati; Marco Vanoni; Lilia Alberghina; Ferdinando Chiaradonna
Journal:  PLoS One       Date:  2009-03-05       Impact factor: 3.240

9.  Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA).

Authors:  K Thangavelu; Qing Yun Chong; Boon Chuan Low; J Sivaraman
Journal:  Sci Rep       Date:  2014-01-23       Impact factor: 4.379

10.  Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.

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Journal:  Cell Metab       Date:  2014-04-01       Impact factor: 27.287
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Review 1.  Proteins moonlighting in tumor metabolism and epigenetics.

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2.  Macrophage mitochondrial fission improves cancer cell phagocytosis induced by therapeutic antibodies and is impaired by glutamine competition.

Authors:  Jiang Li; Yingying Ye; Zhihan Liu; Guoyang Zhang; Huiqi Dai; Jiaqian Li; Boxuan Zhou; Yihong Li; Qiyi Zhao; Jingying Huang; Jingwei Feng; Shu Liu; Peigang Ruan; Jinjing Wang; Jiang Liu; Min Huang; Xinwei Liu; Shubin Yu; Ziyang Liang; Liping Ma; Xiaoxia Gou; Guoliang Zhang; Nian Chen; Yiwen Lu; Can Di; Qidong Xia; Jiayao Pan; Ru Feng; Qingqing Cai; Shicheng Su
Journal:  Nat Cancer       Date:  2022-04-28

Review 3.  Metabolism of Amino Acids in Cancer.

Authors:  Zhen Wei; Xiaoyi Liu; Chunming Cheng; Wei Yu; Ping Yi
Journal:  Front Cell Dev Biol       Date:  2021-01-12

Review 4.  NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications.

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5.  Unveiling Metabolic Vulnerability and Plasticity of Human Osteosarcoma Stem and Differentiated Cells to Improve Cancer Therapy.

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  5 in total

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