Literature DB >> 2991870

Primary hepatocellular carcinoma associated with Wilson's disease in a young woman.

R Guan, C J Oon, P K Wong, W C Foong, A Wee.   

Abstract

A 27 year old woman with hepato-lenticular degeneration (Wilson's disease) was found to have primary hepatocellular carcinoma (PHC) three and a half years after she was started on treatment with D-penicillamine. The tumour was resected since when she has remained well. Her liver function tests were normal throughout the course of her disease. The available literature is reviewed and possible mechanisms for this association proposed.

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Year:  1985        PMID: 2991870      PMCID: PMC2418234          DOI: 10.1136/pgmj.61.714.357

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  13 in total

1.  Hepatolenticular degeneration (Wilson's disease) and juvenile cirrhosis in the same family.

Authors:  T LYGREN
Journal:  Lancet       Date:  1959-02-07       Impact factor: 79.321

2.  Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies.

Authors:  H A EDMONDSON; P E STEINER
Journal:  Cancer       Date:  1954-05       Impact factor: 6.860

3.  [Hepatolenticular degeneration and primary cancer of the liver].

Authors:  P F Girard; A Vachon; M Tommasi; P Paliard; M Rochet; J Barthe
Journal:  Lyon Med       Date:  1968-04-28

4.  Bromocriptine-responsive form of idiopathic oedema.

Authors:  C R Edwards; G M Besser; M O Thorner
Journal:  Lancet       Date:  1979-07-14       Impact factor: 79.321

5.  [Hepatocellular carcinoma and primary biliary cirrhosis: report of one case (author's transl)].

Authors:  L Mallet; J P Petite; D Amat; F Bloch; Y Juillet; J P Camilléri; E Housset
Journal:  Gastroenterol Clin Biol       Date:  1981-04

6.  Long-term therapy of Wilson's disease.

Authors:  A Deiss; R E Lynch; G R Lee; G E Cartwright
Journal:  Ann Intern Med       Date:  1971-07       Impact factor: 25.391

7.  Hepatocellular carcinoma in primary biliary cirrhosis: report of four cases.

Authors:  N Krasner; P J Johnson; B Portmann; G Watkinson; R N Macsween; R Williams
Journal:  Gut       Date:  1979-03       Impact factor: 23.059

8.  Lysosomal defect of hepatic copper excretion in Wilson's disease (hepatolenticular degeneration).

Authors:  I Sternlieb; C J Van den Hamer; A G Morell; S Alpert; G Gregoriadis; I H Scheinberg
Journal:  Gastroenterology       Date:  1973-01       Impact factor: 22.682

9.  Wilson's disease and hepatocellular carcinoma: possible protective role of copper.

Authors:  M L Wilkinson; B Portmann; R Williams
Journal:  Gut       Date:  1983-08       Impact factor: 23.059

10.  The effect of copper acetate on p-dimethylaminoazobenzene carcinogenesis in the rat.

Authors:  J S HOWELL
Journal:  Br J Cancer       Date:  1958-12       Impact factor: 7.640

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  6 in total

1.  Wilson disease: histopathological correlations with treatment on follow-up liver biopsies.

Authors:  Sandy Cope-Yokoyama; Milton J Finegold; Giacomo Carlo Sturniolo; Kyoungmi Kim; Claudia Mescoli; Massimo Rugge; Valentina Medici
Journal:  World J Gastroenterol       Date:  2010-03-28       Impact factor: 5.742

2.  Wilson disease and hepatocellular carcinoma.

Authors:  Ruliang Xu; Cristina H Hajdu
Journal:  Gastroenterol Hepatol (N Y)       Date:  2008-06

3.  Non-viral factors contributing to hepatocellular carcinoma.

Authors:  Manal A Hamed; Sanaa A Ali
Journal:  World J Hepatol       Date:  2013-06-27

4.  Hepatocellular carcinoma in a non-cirrhotic patient with Wilson's disease.

Authors:  Raphael Thattil; Jean-François Dufour
Journal:  World J Gastroenterol       Date:  2013-04-07       Impact factor: 5.742

Review 5.  Non-viral causes of hepatocellular carcinoma.

Authors:  David H Van Thiel; Guiliano Ramadori
Journal:  J Gastrointest Cancer       Date:  2011-12

6.  Wilson disease in 71 patients followed for over two decades in a tertiary center in Saudi Arabia: a retrospective review.

Authors:  Mohammed Al Fadda; Mohammed Al Quaiz; Hamad Al Ashgar; Khalid Al Kahtani; Ahmed Helmy; Ali Al Benmousa; Maheeba Abdulla; Musthafa Peedikayil
Journal:  Ann Saudi Med       Date:  2012 Nov-Dec       Impact factor: 1.526

  6 in total

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