Literature DB >> 29911114

Financial toxicity and implications for cancer care in the era of molecular and immune therapies.

George Tran1, S Yousuf Zafar1,2.   

Abstract

Molecular and immune therapies have revolutionized cancer treatment and improved patient outcomes and survival. However, the pricing of these drugs has become an issue as the cost of cancer care continues to rise significantly. Cost sharing policies have increased out-of-pocket expenses for patients, leading to poorer financial well-being, quality of life, psychosocial health, and treatment adherence. In this review, we briefly examine some factors affecting the pricing of these new targeted therapies; the effects of financial toxicity on patients; and highlight potential health policy and patient-provider level interventions to address these issues.

Entities:  

Keywords:  Cost; drug pricing; financial burden; immuno-oncology; insurance

Year:  2018        PMID: 29911114      PMCID: PMC5985271          DOI: 10.21037/atm.2018.03.28

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  82 in total

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2.  A Time-Trend Economic Analysis of Cancer Drug Trials.

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4.  Relationships Among Financial Distress, Emotional Distress, and Overall Distress in Insured Patients With Cancer.

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Journal:  J Oncol Pract       Date:  2016-06-21       Impact factor: 3.840

5.  Research and Development Spending to Bring a Single Cancer Drug to Market and Revenues After Approval.

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7.  Out-of-pocket costs and oral cancer medication discontinuation in the elderly.

Authors:  Nantana Kaisaeng; Spencer E Harpe; Norman V Carroll
Journal:  J Manag Care Spec Pharm       Date:  2014-07

8.  Cost-Effectiveness Analysis of Regorafenib for Metastatic Colorectal Cancer.

Authors:  Daniel A Goldstein; Bilal B Ahmad; Qiushi Chen; Turgay Ayer; David H Howard; Joseph Lipscomb; Bassel F El-Rayes; Christopher R Flowers
Journal:  J Clin Oncol       Date:  2015-08-24       Impact factor: 44.544

9.  Changes in employment and household income during the 24 months following a cancer diagnosis.

Authors:  Jill A Bennett; Paul Brown; Linda Cameron; Lisa C Whitehead; David Porter; Katherine M McPherson
Journal:  Support Care Cancer       Date:  2008-11-27       Impact factor: 3.603

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Journal:  JAMA Oncol       Date:  2016-09-01       Impact factor: 31.777

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  34 in total

1.  Patient-reported financial toxicity and adverse medical consequences in head and neck cancer.

Authors:  Whitney H Beeler; Emily L Bellile; Keith A Casper; Elizabeth Jaworski; Nicholas J Burger; Kelly M Malloy; Matthew E Spector; Andrew G Shuman; Andrew Rosko; Chaz L Stucken; Steven B Chinn; Aleksandar F Dragovic; Christina H Chapman; Dawn Owen; Shruti Jolly; Carol R Bradford; Mark E P Prince; Francis P Worden; Reshma Jagsi; Michelle L Mierzwa; Paul L Swiecicki
Journal:  Oral Oncol       Date:  2019-12-23       Impact factor: 5.337

2.  Innovating Cancer Care Delivery: the Example of the 4R Oncology Model for Colorectal Cancer Patients.

Authors:  Julia Trosman; Christine Weldon; Sheetal Kircher; William Gradishar; Al Benson
Journal:  Curr Treat Options Oncol       Date:  2019-02-11

3.  Rural-urban differences in financial burden among cancer survivors: an analysis of a nationally representative survey.

Authors:  Whitney E Zahnd; Melinda M Davis; Jason S Rotter; Robin C Vanderpool; Cynthia K Perry; Jackilen Shannon; Linda K Ko; Stephanie B Wheeler; Cassie L Odahowski; Paige E Farris; Jan M Eberth
Journal:  Support Care Cancer       Date:  2019-04-10       Impact factor: 3.603

Review 4.  Decision-analytic modeling as a tool for selecting optimal therapy incorporating hematopoietic stem cell transplantation in patients with hematological malignancy.

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5.  The Impact of Financial Toxicity on Psychological Well-Being, Coping Self-Efficacy, and Cost-Coping Behaviors in Young Adults with Cancer.

Authors:  Bridgette Thom; Catherine Benedict
Journal:  J Adolesc Young Adult Oncol       Date:  2019-02-28       Impact factor: 2.223

6.  General Health Care Utilization Among Nonelderly Cancer Survivors Before and After Affordable Care Act Implementation: Early Results.

Authors:  Amy L Shaver; Ying Cao; Katia Noyes
Journal:  JCO Oncol Pract       Date:  2020-02-18

Review 7.  Financial toxicity associated with treatment of localized prostate cancer.

Authors:  Brandon S Imber; Melissa Varghese; Behfar Ehdaie; Daniel Gorovets
Journal:  Nat Rev Urol       Date:  2019-12-02       Impact factor: 14.432

8.  Age-Related Differences in Financial Toxicity and Unmet Resource Needs Among Adolescent and Young Adult Cancer Patients.

Authors:  Heydon K Kaddas; Samantha T Pannier; Karely Mann; Austin R Waters; Sara Salmon; Tomoko Tsukamoto; Echo L Warner; Brynn Fowler; Mark A Lewis; Douglas B Fair; Anne C Kirchhoff
Journal:  J Adolesc Young Adult Oncol       Date:  2019-09-16       Impact factor: 2.223

Review 9.  Breast Cancer: Reimbursement Policies and Adoption of New Therapeutic Agents by National Health Systems.

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Journal:  Breast Care (Basel)       Date:  2019-09-24       Impact factor: 2.860

10.  Testing microsatellite instability in solid tumors: the ideal versus what is real.

Authors:  Virgilio Souza E Silva; Louise De Brot; Rachel P Riechelmann
Journal:  Ann Transl Med       Date:  2019-11
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