Literature DB >> 29903759

L-leucine increases translation of RPS14 and LARP1 in erythroblasts from del(5q) myelodysplastic syndrome patients.

Erica Bello1, Jonathan Kerry2, Shalini Singh1, Bon Ham Yip1, Rajko Kušec3, Sally Killick4, Sophie Raynaud5, Jacqueline Boultwood6, Andrea Pellagatti6.   

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Year:  2018        PMID： 29903759      PMCID： PMC6278984          DOI： 10.3324/haematol.2018.190447

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  15 in total

1.  Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.

Authors:  B H Yip; A Pellagatti; C Vuppusetty; A Giagounidis; U Germing; A A Lamikanra; D J Roberts; M Fernandez-Mercado; E-J McDonald; S Killick; J S Wainscoat; J Boultwood
Journal:  Leukemia       Date:  2012-03-20       Impact factor: 11.528

2.  Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.

Authors:  B H Yip; C Vuppusetty; M Attwood; A Giagounidis; U Germing; A A Lamikanra; D J Roberts; J P Maciejewski; P Vandenberghe; C Mecucci; J S Wainscoat; A Pellagatti; J Boultwood
Journal:  Leukemia       Date:  2013-01-22       Impact factor: 11.528

3.  L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.

Authors:  Elspeth M Payne; Maria Virgilio; Anupama Narla; Hong Sun; Michelle Levine; Barry H Paw; Nancy Berliner; A Thomas Look; Benjamin L Ebert; Arati Khanna-Gupta
Journal:  Blood       Date:  2012-06-25       Impact factor: 22.113

4.  Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.

Authors:  Shilpee Dutt; Anupama Narla; Katherine Lin; Ann Mullally; Nirmalee Abayasekara; Christine Megerdichian; Frederick H Wilson; Treeve Currie; Arati Khanna-Gupta; Nancy Berliner; Jeffery L Kutok; Benjamin L Ebert
Journal:  Blood       Date:  2010-11-10       Impact factor: 22.113

5.  Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.

Authors:  Pekka Jaako; Shubhranshu Debnath; Karin Olsson; David Bryder; Johan Flygare; Stefan Karlsson
Journal:  Blood       Date:  2012-07-12       Impact factor: 22.113

6.  LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.

Authors:  Sungki Hong; Mallory A Freeberg; Ting Han; Avani Kamath; Yao Yao; Tomoko Fukuda; Tsukasa Suzuki; John K Kim; Ken Inoki
Journal:  Elife       Date:  2017-06-26       Impact factor: 8.140

7.  A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

Authors:  Jillian L Barlow; Lesley F Drynan; Duncan R Hewett; Luke R Holmes; Silvia Lorenzo-Abalde; Alison L Lane; Helen E Jolin; Richard Pannell; Angela J Middleton; See Heng Wong; Alan J Warren; James S Wainscoat; Jacqueline Boultwood; Andrew N J McKenzie
Journal:  Nat Med       Date:  2009-11-22       Impact factor: 53.440

Review 8.  Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.

Authors:  Jacqueline Boultwood; Bon Ham Yip; Chaitanya Vuppusetty; Andrea Pellagatti; James S Wainscoat
Journal:  Adv Biol Regul       Date:  2012-09-13

9.  Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes.

Authors:  Andrea Pellagatti; Eva Hellström-Lindberg; Aristoteles Giagounidis; Janet Perry; Luca Malcovati; Matteo G Della Porta; Martin Jädersten; Sally Killick; Carrie Fidler; Mario Cazzola; James S Wainscoat; Jacqueline Boultwood
Journal:  Br J Haematol       Date:  2008-05-08       Impact factor: 6.998

10.  Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19.

Authors:  Y Zhang; J Ear; Z Yang; K Morimoto; B Zhang; S Lin
Journal:  Cell Death Dis       Date:  2014-07-24       Impact factor: 8.469
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