Literature DB >> 23337929

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.

B H Yip, C Vuppusetty, M Attwood, A Giagounidis, U Germing, A A Lamikanra, D J Roberts, J P Maciejewski, P Vandenberghe, C Mecucci, J S Wainscoat, A Pellagatti, J Boultwood.   

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Year:  2013        PMID： 23337929     DOI： 10.1038/leu.2013.20

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  5 in total

1.  L-leucine increases translation of RPS14 and LARP1 in erythroblasts from del(5q) myelodysplastic syndrome patients.

Authors:  Erica Bello; Jonathan Kerry; Shalini Singh; Bon Ham Yip; Rajko Kušec; Sally Killick; Sophie Raynaud; Jacqueline Boultwood; Andrea Pellagatti
Journal:  Haematologica       Date:  2018-06-14       Impact factor: 9.941

Review 2.  Recent Advances in the 5q- Syndrome.

Authors:  Andrea Pellagatti; Jacqueline Boultwood
Journal:  Mediterr J Hematol Infect Dis       Date:  2015-05-20       Impact factor: 2.576

Review 3.  The Role of mTOR Inhibitors in Hematologic Disease: From Bench to Bedside.

Authors:  Yimei Feng; Xiaoli Chen; Kaniel Cassady; Zhongmin Zou; Shijie Yang; Zheng Wang; Xi Zhang
Journal:  Front Oncol       Date:  2021-01-08       Impact factor: 6.244

Review 4.  Eukaryotic ribosome quality control system: a potential therapeutic target for human diseases.

Authors:  Peng-Yue Zhao; Ren-Qi Yao; Zi-Cheng Zhang; Sheng-Yu Zhu; Yu-Xuan Li; Chao Ren; Xiao-Hui Du; Yong-Ming Yao
Journal:  Int J Biol Sci       Date:  2022-03-14       Impact factor: 6.580

5.  Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors.

Authors:  Rui Liu; Valentina Iadevaia; Julien Averous; Peter M Taylor; Ze Zhang; Christopher G Proud
Journal:  Nucleic Acids Res       Date:  2014-02-13       Impact factor: 16.971
  5 in total

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