Literature DB >> 2989652

Stimulation by lipoxygenase products of superoxide anion production in FMLP-treated neutrophils.

J K Beckman, J C Gay, A R Brash, J N Lukens, J A Oates.   

Abstract

Our recent observation that leukotriene B4 (10(-9)M) is a potent enhancer of FMLP-initiated neutrophil superoxide anion formation prompted an evaluation of the ability of other lipoxygenase products and related compounds to modulate this response. The results indicate that FMLP-evoked O-2 may be enhanced by 10(-8)-10(-7)M levels of a number of lipids, in addition to LTB4, including 5-HPETE, 5-HETE, 5,15-DiHPETE and by higher levels of other 15-series lipoxygenase products and arachidonic acid. It is of interest that the relative potency of these agents in potentiating the superoxide response to FMLP approximately parallels their reported ability to induce chemotactic activity in leukocytes.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2989652     DOI： 10.1007/bf02534265

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  17 in total

1.  Spectrum of horse-heart cytochrome c.

Authors:  E MARGOLIASH; N FROHWIRT
Journal:  Biochem J       Date:  1959-03       Impact factor: 3.857

2.  Novel leukotrienes: products formed by initial oxygenation of arachidonic acid at C-15.

Authors:  W Jubiz; O Rådmark; J A Lindgren; C Malmsten; B Samuelsson
Journal:  Biochem Biophys Res Commun       Date:  1981-04-15       Impact factor: 3.575

3.  Modulation of human neutrophil function by monohydroxy-eicosatetraenoic acids.

Authors:  E J Goetzl; A R Brash; A I Tauber; J A Oates; W C Hubbard
Journal:  Immunology       Date:  1980-04       Impact factor: 7.397

4.  Neutrophil degranulation responses to combinations of arachidonate metabolites and platelet-activating factor.

Authors:  J T O'Flaherty; R L Wykle; M J Thomas; C E McCall
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1984-01

5.  Vitamin E modulates the lipoxygenation of arachidonic acid in leukocytes.

Authors:  E J Goetzl
Journal:  Nature       Date:  1980-11-13       Impact factor: 49.962

6.  cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils.

Authors:  J A Badwey; J T Curnutte; M L Karnovsky
Journal:  J Biol Chem       Date:  1981-12-25       Impact factor: 5.157

7.  A second pathway of leukotriene biosynthesis in porcine leukocytes.

Authors:  R L Maas; A R Brash; J A Oates
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

8.  5-L-hydroxy-6,8,11,14-eicosatetraenoate potentiates the human neutrophil degranulating action of platelet-activating factor.

Authors:  J T O'Flaherty; M J Thomas; M J Hammett; C Carroll; C E McCall; R L Wykle
Journal:  Biochem Biophys Res Commun       Date:  1983-02-28       Impact factor: 3.575

9.  Inhibition by prostaglandins of leukotriene B4 release from activated neutrophils.

Authors:  E A Ham; D D Soderman; M E Zanetti; H W Dougherty; E McCauley; F A Kuehl
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

10.  Evidence for a lipoxygenase mechanism in the biosynthesis of epoxide and dihydroxy leukotrienes from 15(S)-hydroperoxyicosatetraenoic acid by human platelets and porcine leukocytes.

Authors:  R L Maas; A R Brash
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205
View more
  5 in total

1.  Cytotoxic enzyme release and oxygen centered radical formation in human neutrophils are selectively inhibited by E-type prostaglandins but not by PGI2.

Authors:  G Hecker; P Ney; K Schrör
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-04       Impact factor: 3.000

2.  Three new and bioactive icosanoids from the temperate red marine alga Farlowia mollis.

Authors:  M L Solem; Z D Jiang; W H Gerwick
Journal:  Lipids       Date:  1989-04       Impact factor: 1.880

Review 3.  Chemotactic peptides. Mechanisms, functions, and possible role in inflammatory bowel disease.

Authors:  C C Nast; L E LeDuc
Journal:  Dig Dis Sci       Date:  1988-03       Impact factor: 3.199

4.  Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection.

Authors:  Stephen R Clark; Christopher J Guy; Martin J Scurr; Philip R Taylor; Ann P Kift-Morgan; Victoria J Hammond; Christopher P Thomas; Barbara Coles; Gareth W Roberts; Matthias Eberl; Simon A Jones; Nicholas Topley; Sailesh Kotecha; Valerie B O'Donnell
Journal:  Blood       Date:  2010-12-21       Impact factor: 22.113

5.  5-Hydroxyeicosanoids selectively stimulate the human neutrophil 15-lipoxygenase to use endogenous substrate.

Authors:  R C Nichols; J Y Vanderhoek
Journal:  J Exp Med       Date:  1990-02-01       Impact factor: 14.307
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.