Literature DB >> 2989551

Nucleotide sequence and structural features of a novel US-a junction present in a defective herpes simplex virus genome.

E S Mocarski, L P Deiss, N Frenkel.   

Abstract

Defective genomes generated during serial propagation of herpes simplex virus type 1 (Justin) consist of tandem reiterations of sequences that are colinear with a portion of the S component of the standard viral genome. We determined the structure of the novel US-a junction, at which the US sequences of one repeat unit join the a sequences of the adjacent repeat unit. Comparison of the nucleotide sequence at this junction with the nucleotide sequence of the corresponding US region of the standard virus genome indicated that the defective genome repeat unit arose by a single recombinational event between an L-S junction a sequence and the US region. The recombinational process might have been mediated by limited sequence homology. The sequences retained within the US-a junction further define the signal for cleavage and packaging of viral DNA.

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Year:  1985        PMID： 2989551      PMCID： PMC254908     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  31 in total

1.  Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid.

Authors:  A C Chang; S N Cohen
Journal:  J Bacteriol       Date:  1978-06       Impact factor: 3.490

2.  Structure and origin of defective genomes contained in serially passaged herpes simplex virus type 1 (Justin).

Authors:  H Locker; N Frenkel
Journal:  J Virol       Date:  1979-03       Impact factor: 5.103

Review 3.  The structure and isomerization of herpes simplex virus genomes.

Authors:  B Roizman
Journal:  Cell       Date:  1979-03       Impact factor: 41.582

4.  Origin of two different classes of defective HSV-1 Angelotti DNA.

Authors:  H C Kaerner; I B Maichle; A Ott; C H Schröder
Journal:  Nucleic Acids Res       Date:  1979-04       Impact factor: 16.971

5.  Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them.

Authors:  N Frenkel; R J Jacob; R W Honess; G S Hayward; H Locker; B Roizman
Journal:  J Virol       Date:  1975-07       Impact factor: 5.103

6.  Molecular engineering of the herpes simplex virus genome: insertion of a second L-S junction into the genome causes additional genome inversions.

Authors:  E S Mocarski; L E Post; B Roizman
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

7.  Cloning of reiterated and nonreiterated herpes simplex virus 1 sequences as BamHI fragments.

Authors:  L E Post; A J Conley; E S Mocarski; B Roizman
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

8.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

9.  BamI, KpnI, and SalI restriction enzyme maps of the DNAs of herpes simplex virus strains Justin and F: occurrence of heterogeneities in defined regions of the viral DNA.

Authors:  H Locker; N Frenkel
Journal:  J Virol       Date:  1979-11       Impact factor: 5.103

10.  Anatomy of herpes simplex virus DNA. VI. Defective DNA originates from the S component.

Authors:  N Frenkeĺ; H Locker; W Batterson; G S Hayward; B Roizman
Journal:  J Virol       Date:  1976-11       Impact factor: 5.103
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  24 in total

1.  Herpes simplex virus DNA packaging sequences adopt novel structures that are specifically recognized by a component of the cleavage and packaging machinery.

Authors:  K Adelman; B Salmon; J D Baines
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

2.  Recombination of the internal direct repeat element DR2 responsible for the fluidity of the a sequence of herpes simplex virus type 1.

Authors:  K Umene
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103

3.  Reassessing the organization of the UL42-UL43 region of the human cytomegalovirus strain AD169 genome.

Authors:  E S Mocarski; M N Prichard; C S Tan; J M Brown
Journal:  Virology       Date:  1997-12-08       Impact factor: 3.616

4.  Characterization of DNA sequence-common and sequence-specific proteins binding to cis-acting sites for cleavage of the terminal a sequence of the herpes simplex virus 1 genome.

Authors:  J Chou; B Roizman
Journal:  J Virol       Date:  1989-03       Impact factor: 5.103

5.  Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs.

Authors:  A D Kwong; N Frenkel
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

6.  A host cell protein binds to a highly conserved sequence element (pac-2) within the cytomegalovirus a sequence.

Authors:  G W Kemble; E S Mocarski
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

7.  Herpes simplex virus type 1 recombination: the Uc-DR1 region is required for high-level a-sequence-mediated recombination.

Authors:  R E Dutch; B V Zemelman; I R Lehman
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

8.  Herpes simplex virus type 1 DNA replication is specifically required for high-frequency homologous recombination between repeated sequences.

Authors:  R E Dutch; V Bianchi; I R Lehman
Journal:  J Virol       Date:  1995-05       Impact factor: 5.103

9.  Epstein-Barr virus intrastrain recombination in oral hairy leukoplakia.

Authors:  D M Walling; N Raab-Traub
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

10.  Excision of DNA fragments corresponding to the unit-length a sequence of herpes simplex virus type 1 and terminus variation predominate on one side of the excised fragment.

Authors:  K Umene
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103
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