Literature DB >> 2989411

Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.

W C Greene, R J Robb, P B Svetlik, C M Rusk, J M Depper, W J Leonard.   

Abstract

Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation, and (c) expressed low affinity but not high affinity receptors for IL-2.

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Year:  1985        PMID: 2989411      PMCID: PMC2187706          DOI: 10.1084/jem.162.1.363

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  18 in total

1.  A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

Authors:  T Uchiyama; S Broder; T A Waldmann
Journal:  J Immunol       Date:  1981-04       Impact factor: 5.422

2.  A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor.

Authors:  W J Leonard; J M Depper; T Uchiyama; K A Smith; T A Waldmann; W C Greene
Journal:  Nature       Date:  1982-11-18       Impact factor: 49.962

Review 3.  T-cell growth factor.

Authors:  K A Smith
Journal:  Immunol Rev       Date:  1980       Impact factor: 12.988

4.  Altering genotype and phenotype by DNA-mediated gene transfer.

Authors:  A Pellicer; D Robins; B Wold; R Sweet; J Jackson; I Lowy; J M Roberts; G K Sim; S Silverstein; R Axel
Journal:  Science       Date:  1980-09-19       Impact factor: 47.728

5.  Characterization of human interleukin 2 receptor (Tac antigen) in normal and leukemic T cells: co-expression of normal and aberrant receptors on Hut-102 cells.

Authors:  Y Wano; T Uchiyama; K Fukui; M Maeda; H Uchino; J Yodoi
Journal:  J Immunol       Date:  1984-06       Impact factor: 5.422

6.  Characterization of the human receptor for T-cell growth factor.

Authors:  W J Leonard; J M Depper; R J Robb; T A Waldmann; W C Greene
Journal:  Proc Natl Acad Sci U S A       Date:  1983-11       Impact factor: 11.205

7.  Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

Authors:  R J Robb; W C Greene; C M Rusk
Journal:  J Exp Med       Date:  1984-10-01       Impact factor: 14.307

8.  Purification and partial sequence analysis of human T-cell growth factor.

Authors:  R J Robb; R M Kutny; V Chowdhry
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

9.  T cell growth factor receptors. Quantitation, specificity, and biological relevance.

Authors:  R J Robb; A Munck; K A Smith
Journal:  J Exp Med       Date:  1981-11-01       Impact factor: 14.307

10.  Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen.

Authors:  R J Robb; W C Greene
Journal:  J Exp Med       Date:  1983-10-01       Impact factor: 14.307

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  30 in total

1.  Flow cytometry resonance energy transfer suggests an association between low-affinity interleukin 2 binding sites and HLA class I molecules.

Authors:  A Harel-Bellan; P Krief; L Rimsky; W L Farrar; Z Mishal
Journal:  Biochem J       Date:  1990-05-15       Impact factor: 3.857

2.  Molecular basis for two different affinity states of the interleukin 2 receptor: affinity conversion model.

Authors:  S Kondo; A Shimizu; Y Saito; M Kinoshita; T Honjo
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

3.  Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

Authors:  M Tsudo; R W Kozak; C K Goldman; T A Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

4.  The human interleukin-2 receptor beta-chain gene: genomic organization, promoter analysis and chromosomal assignment.

Authors:  H Shibuya; M Yoneyama; Y Nakamura; H Harada; M Hatakeyama; S Minamoto; T Kono; T Doi; R White; T Taniguchi
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

5.  Conversion of low-affinity interleukin 2 receptors to a high-affinity state following fusion of cell membranes.

Authors:  R J Robb
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

6.  Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies.

Authors:  M Tsudo; F Kitamura; M Miyasaka
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

7.  Abnormal intracellular sorting of O-linked carbohydrate-deficient interleukin-2 receptors.

Authors:  K F Kozarsky; S M Call; S K Dower; M Krieger
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

Review 8.  Regulation of lymphocyte growth by antagonists of interleukin-2 or its cellular receptor.

Authors:  G N Gaulton; J F Markmann
Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

9.  Cooperative interactions between the interleukin 2 receptor alpha and beta chains alter the interleukin 2-binding affinity of the receptor subunits.

Authors:  E Roessler; A Grant; G Ju; M Tsudo; K Sugamura; T A Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-12       Impact factor: 11.205

10.  Leukotriene B4 augments interleukin-2 receptor-beta (IL-2R beta) expression and IL-2R beta-mediated cytotoxic response in human peripheral blood lymphocytes.

Authors:  J Stanková; N Gagnon; M Rola-Pleszczynski
Journal:  Immunology       Date:  1992-06       Impact factor: 7.397

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