Literature DB >> 2989050

"Cytoplasmic" islet cell antibodies. Evidence that the target antigen is a sialoglycoconjugate.

R C Nayak, M A Omar, A Rabizadeh, S Srikanta, G S Eisenbarth.   

Abstract

We have biochemically treated (periodate, borohydride, neuraminidase, organic solvents) frozen sections of human pancreas and studied the reactivity of islet-cell-antibody-positive human sera and monoclonal antibodies. The autoantigen of pancreatic sections has the properties of sialic acid containing glycolipid.

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Year:  1985        PMID: 2989050     DOI: 10.2337/diab.34.6.617

Source DB:  PubMed          Journal:  Diabetes        ISSN: 0012-1797            Impact factor:   9.461


  25 in total

1.  IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.

Authors:  M S Lan; C Wasserfall; N K Maclaren; A L Notkins
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

Review 2.  Prediction and prevention of type I diabetes.

Authors:  R Gianani; G S Eisenbarth
Journal:  J Endocrinol Invest       Date:  1994 Jul-Aug       Impact factor: 4.256

3.  Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products.

Authors:  C Boitard; M C Villa; C Becourt; H P Gia; C Huc; P Sempe; M M Portier; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

Review 4.  Mechanisms of autoimmunity in insulin-dependent diabetes mellitus.

Authors:  J F Bach
Journal:  Clin Exp Immunol       Date:  1988-04       Impact factor: 4.330

5.  Antibodies to a Mr-64,000 islet cell protein in Swedish children with newly diagnosed type 1 (insulin-dependent) diabetes.

Authors:  M Christie; M Landin-Olsson; G Sundkvist; G Dahlquist; A Lernmark; S Baekkeskov
Journal:  Diabetologia       Date:  1988-08       Impact factor: 10.122

Review 6.  Islet cell autoantigens in insulin-dependent diabetes.

Authors:  M A Atkinson; N K Maclaren
Journal:  J Clin Invest       Date:  1993-10       Impact factor: 14.808

7.  Production and characterization of a monoclonal islet cell surface autoantibody from the BB rat.

Authors:  C H Brogren; F Hirsch; P Wood; P Druet; P Poussier
Journal:  Diabetologia       Date:  1986-05       Impact factor: 10.122

Review 8.  The role of immunotherapy in type I diabetes mellitus.

Authors:  M E Geffner; B M Lippe
Journal:  West J Med       Date:  1987-03

9.  Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen.

Authors:  W Richter; J Endl; T H Eiermann; M Brandt; R Kientsch-Engel; C Thivolet; H Jungfer; W A Scherbaum
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-15       Impact factor: 11.205

10.  Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies.

Authors:  W Richter; T H Eiermann; J Endl; J Seissler; S Wolfahrt; M Brandt; H Jungfer; W A Scherbaum
Journal:  Diabetologia       Date:  1993-08       Impact factor: 10.122

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