Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Detailed analysis of the mRNAs mapping in the short unique region of herpes simplex virus type 1.

Literature DB >> 2987814

Detailed analysis of the mRNAs mapping in the short unique region of herpes simplex virus type 1.

Abstract

We have analysed the mRNAs which map within the short unique (US) region of the herpes simplex virus type 1 (HSV-1) genome. US has a total length of 12979 base pairs (1) and is extensively transcribed with approximately 94% of the total sequence present in cytoplasmic mRNAs and 79% of the total sequence considered to be protein coding. There are several examples of overlapping functions and multiple use of DNA sequence within this region. US contains 12 genes (1) which are expressed as 13 mRNAs. Two of these mRNAs are thought to arise from the same gene since they differ only slightly in the positions of their 5' ends and probably specify the same polypeptide. 11 of the 13 mRNAs are arranged into four nested families with unique 5' ends and common 3' co-termini. The other two mRNAs have unique 5' and 3' ends.

Entities: Species

Mesh：

Substances：

Year: 1985 PMID： 2987814 PMCID： PMC341045 DOI： 10.1093/nar/13.3.953

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

41 in total

1. Recombinants between herpes simplex virus types 1 and 2: analyses of genome structures and expression of immediate early polypeptides.

Authors: V G Preston; A J Davison; H S Marsden; M C Timbury; J H Subak-Sharpe; N M Wilkie
Journal: J Virol Date: 1978-11 Impact factor: 5.103

2. Physical mapping of herpes simplex virus-induced polypeptides.

Authors: H S Marsden; N D Stow; V G Preston; M C Timbury; N M Wilkie
Journal: J Virol Date: 1978-11 Impact factor: 5.103

3. Temporal regulation of herpes simplex virus type 1 transcription: location of transcripts on the viral genome.

Authors: J B Clements; R J Watson; N M Wilkie
Journal: Cell Date: 1977-09 Impact factor: 41.582

4. Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants.

Authors: L S Morse; L Pereira; B Roizman; P A Schaffer
Journal: J Virol Date: 1978-05 Impact factor: 5.103

5. Complete nucleotide sequence of SV40 DNA.

Authors: W Fiers; R Contreras; G Haegemann; R Rogiers; A Van de Voorde; H Van Heuverswyn; J Van Herreweghe; G Volckaert; M Ysebaert
Journal: Nature Date: 1978-05-11 Impact factor: 49.962

6. Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of infected cells.

Authors: W T Ruyechan; L S Morse; D M Knipe; B Roizman
Journal: J Virol Date: 1979-02 Impact factor: 5.103

7. Adenovirus-2 messengers--an example of baroque molecular architecture.

Authors: T R Broker; L T Chow; A R Dunn; R E Gelinas; J A Hassell; D F Klessig; J B Lewis; R J Roberts; B S Zain
Journal: Cold Spring Harb Symp Quant Biol Date: 1978

8. A tandemly reiterated DNA sequence in the long repeat region of herpes simplex virus type 1 found in close proximity to immediate-early mRNA 1.

Authors: F J Rixon; M E Campbell; J B Clements
Journal: J Virol Date: 1984-11 Impact factor: 5.103

9. A membrane-filter technique for the detection of complementary DNA.

Authors: D T Denhardt
Journal: Biochem Biophys Res Commun Date: 1966-06-13 Impact factor: 3.575

10. Structure of the adenovirus 2 early mRNAs.

Authors: A J Berk; P A Sharp
Journal: Cell Date: 1978-07 Impact factor: 41.582

26 in total

1. Phylogenetic analysis of varicella-zoster virus: evidence of intercontinental spread of genotypes and recombination.

Authors: Winsome Barrett Muir; Richard Nichols; Judith Breuer
Journal: J Virol Date: 2002-02 Impact factor: 5.103

2. Detection of herpes simplex virus type 1 transcripts during latent infection in mice.

Authors: J G Spivack; N W Fraser
Journal: J Virol Date: 1987-12 Impact factor: 5.103

3. Regulation of glycoprotein D synthesis: does alpha 4, the major regulatory protein of herpes simplex virus 1, regulate late genes both positively and negatively?

Authors: M Arsenakis; G Campadelli-Fiume; B Roizman
Journal: J Virol Date: 1988-01 Impact factor: 5.103

4. Identification of a new glycoprotein of herpes simplex virus type 1 and genetic mapping of the gene that codes for it.

Authors: D D Richman; A Buckmaster; S Bell; C Hodgman; A C Minson
Journal: J Virol Date: 1986-02 Impact factor: 5.103

5. Alphaherpesviruses possess a gene homologous to the protein kinase gene family of eukaryotes and retroviruses.

Authors: D J McGeoch; A J Davison
Journal: Nucleic Acids Res Date: 1986-02-25 Impact factor: 16.971

6. Characterization and nucleotide sequence of two herpes simplex virus 1 genes whose products modulate alpha-trans-inducing factor-dependent activation of alpha genes.

Authors: J L McKnight; P E Pellett; F J Jenkins; B Roizman
Journal: J Virol Date: 1987-04 Impact factor: 5.103

7. Transcription initiation sites and nucleotide sequence of a herpes simplex virus 1 gene conserved in the Epstein-Barr virus genome and reported to affect the transport of viral glycoproteins.

Authors: P E Pellett; F J Jenkins; M Ackermann; M Sarmiento; B Roizman
Journal: J Virol Date: 1986-12 Impact factor: 5.103

8. Regulation of transcription in vitro from herpes simplex virus genes.

Authors: L I Pizer; D G Tedder; J L Betz; K W Wilcox; P Beard
Journal: J Virol Date: 1986-12 Impact factor: 5.103

9. Insertions in the gG gene of pseudorabies virus reduce expression of the upstream Us3 protein and inhibit cell-to-cell spread of virus infection.

Authors: G L Demmin; A C Clase; J A Randall; L W Enquist; B W Banfield
Journal: J Virol Date: 2001-11 Impact factor: 5.103

10. Transcriptional analyses of the unique short segment of EHV-1 strain Kentucky A.

Authors: C F Colle; D J O'Callaghan
Journal: Virus Genes Date: 1995-02 Impact factor: 2.332