Literature DB >> 29871957

Serious life-threatening multifocal infection in a child, caused by Panton-Valentine leucocidin-producing Staphylococcus aureus (PVL-MSSA).

Neda Irenji1, Suresh Kumar Gopala Pillai2, Jennifer Susan West-Jones3.   

Abstract

Groin pain is a frequently occurring complaint in presentations to the Emergency Department. Muscular sprain is often a differential diagnosis, however serious conditions such as pyomyositis should not be ignored. This case report presents a child with atraumatic right groin pain, which was initially diagnosed as a muscular sprain. The patient later re-presented out of hours to the Emergency Department with what was found to be extensive pelvic abscesses. He was subsequently found to have bilateral pneumonia and later developed a pericardial effusion and osteomyelitis of the right iliac bone, sacroiliac joint and sacrum. With multiple surgical interventions and appropriate antibiotics, he made a full recovery and was discharged home after a total admission time of 41 days. The causative organism was found to be Panton-Valentine leucocidin-positive methicillin-susceptible Staphylococcus aureus. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  bone and joint infections; emergency medicine; infections; orthopaedic and trauma surgery; paediatrics (drugs and medicines)

Mesh:

Substances:

Year:  2018        PMID: 29871957      PMCID: PMC5990082          DOI: 10.1136/bcr-2017-222138

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

1.  PVL positive Staphylococcus aureus skin infections.

Authors:  A Fogo; N Kemp; R Morris-Jones
Journal:  BMJ       Date:  2011-09-09

Review 2.  Clinical management of Staphylococcus aureus bacteremia: a review.

Authors:  Thomas L Holland; Christopher Arnold; Vance G Fowler
Journal:  JAMA       Date:  2014-10-01       Impact factor: 56.272

Review 3.  Panton-Valentine leukocidin osteomyelitis in children: a growing threat.

Authors:  Hassaan Q Sheikh; Adeel Aqil; Andrew Kirby; Fahad S Hossain
Journal:  Br J Hosp Med (Lond)       Date:  2015-01       Impact factor: 0.825

4.  Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients.

Authors:  Yves Gillet; Bertrand Issartel; Philippe Vanhems; Jean-Christophe Fournet; Gerard Lina; Michèle Bes; François Vandenesch; Yves Piémont; Nicole Brousse; Daniel Floret; Jerome Etienne
Journal:  Lancet       Date:  2002-03-02       Impact factor: 79.321

5.  Community-acquired necrotizing pneumonia due to methicillin-sensitive Staphylococcus aureus secreting Panton-Valentine leukocidin: a review of case reports.

Authors:  Lukas Kreienbuehl; Emmanuel Charbonney; Philippe Eggimann
Journal:  Ann Intensive Care       Date:  2011-12-22       Impact factor: 6.925

Review 6.  Basis of virulence in community-associated methicillin-resistant Staphylococcus aureus.

Authors:  Michael Otto
Journal:  Annu Rev Microbiol       Date:  2010       Impact factor: 15.500

Review 7.  Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management.

Authors:  Steven Y C Tong; Joshua S Davis; Emily Eichenberger; Thomas L Holland; Vance G Fowler
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

8.  Panton-Valentine leukocidin Staphylococcus causing fatal necrotising pneumonia in a young boy.

Authors:  Shahzad Haider; David Wright
Journal:  BMJ Case Rep       Date:  2013-03-14

9.  Methicillin sensitive Staphylococcus aureus producing Panton-Valentine leukocidin toxin in Trinidad & Tobago: a case report.

Authors:  Patrick E Akpaka; Stefan Monecke; William H Swanston; Av Chalapathi Rao; Renee Schulz; Paul N Levett
Journal:  J Med Case Rep       Date:  2011-04-20

10.  Outbreak of Skin Infections Due to Panton-Valentine Leukocidin-Positive Methicillin-Susceptible Staphylococcus aureus in a French Prison in 2010-2011.

Authors:  Céline Bourigault; Stéphane Corvec; Virginie Brulet; Pierre-Yves Robert; Olivier Mounoury; Chloé Goubin; David Boutoille; Bruno Hubert; Michèle Bes; Anne Tristan; Jérôme Etienne; Didier Lepelletier
Journal:  PLoS Curr       Date:  2014-03-07
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  2 in total

1.  Paediatric and adult patients from New Caledonia Island admitted to the ICU for community-acquired Panton-Valentine leucocidin-producing Staphylococcus aureus infections.

Authors:  O Imauven; J Colot; E Couadau; P-H Moury; A Preault; F Vincent; Philippe Montravers
Journal:  Sci Rep       Date:  2022-06-30       Impact factor: 4.996

Review 2.  Panton-valentine leukocidin Staphylococcus aureus severe infection in an infant: a case report and a review of the literature.

Authors:  Massimo Luca Castellazzi; Samantha Bosis; Irene Borzani; Claudia Tagliabue; Raffaella Pinzani; Paola Marchisio; Giada Maria di Pietro
Journal:  Ital J Pediatr       Date:  2021-07-17       Impact factor: 2.638

  2 in total

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