| Literature DB >> 2986717 |
S Cockcroft, J A Taylor, J D Judah.
Abstract
The subcellular distribution of the enzymes which phosphorylate phosphatidylinositol sequentially to form phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate was investigated in rat liver. We demonstrate that whilst phosphatidylinositol kinase is present in Golgi, lysosomes and plasma membranes, the kinase that forms phosphatidylinositol 4,5-bisphosphate is localised predominantly at the plasma membrane. The role of the inositol lipid kinases in cell function is discussed.Entities:
Mesh：
Substances：
Year: 1985 PMID： 2986717 DOI： 10.1016/0167-4889(85)90173-9
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002