| Literature DB >> 2998339 |
Abstract
Treatment of chicken erythrocytes with ionophore A23187 and Ca2+ caused the breakdown of a large proportion of the cellular polyphosphoinositides. Since no diacylglycerol or phosphatidate was generated, but there was a small increase in the level of phosphatidylinositol, it was concluded that breakdown occurred as a result of phosphomonoesterase activation. Experiments with subcellular fractions showed that the phosphomonoesterase activity was present in the cytosolic fraction of the cells.Entities:
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Year: 1985 PMID: 2998339 PMCID: PMC1152719 DOI: 10.1042/bj2310179
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857