Literature DB >> 29866597

Constipation in Children with Autism Spectrum Disorder Associated with Increased Emergency Department Visits and Inpatient Admissions.

Brandon Sparks1, Jennifer Cooper2, Caitlin Hayes3, Kent Williams3.   

Abstract

OBJECTIVE: To evaluate whether constipation in children with autism spectrum disorder (ASD) is associated with increased emergency department (ED) visits and inpatient admissions compared with constipation in children without ASD. STUDY
DESIGN: The Nationwide Emergency Department Sample was used to retrospectively examine demographic data, clinical characteristics, and outcomes of children with ASD and children without ASD who visited the ED for constipation between 2006 and 2014.
RESULTS: ED visits by children with ASD were more likely to be constipation-related compared with visits by children with other chronic conditions or children with no chronic conditions (1.9% vs 0.6% vs 0.9%; P < .001). Children with ASD were more likely than children with other chronic conditions or no chronic conditions to be admitted to the hospital after an ED visit for constipation (15.0% vs 10.6% vs 1.2%; P < .001). Hospital charges were higher in children with ASD than in those without chronic conditions.
CONCLUSIONS: Constipation is responsible for a large proportion of ED visits and more inpatient admissions resulting from these ED visits. These findings suggest a need for developing more effective outpatient therapies for constipation in children with ASD.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  autism spectrum disorder; constipation; emergency department

Mesh:

Year:  2018        PMID: 29866597     DOI: 10.1016/j.jpeds.2018.05.004

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  7 in total

1.  Co-occurring medical conditions among individuals with ASD-associated disruptive mutations.

Authors:  Evangeline C Kurtz-Nelson; Jennifer S Beighley; Caitlin M Hudac; Jennifer Gerdts; Arianne S Wallace; Kendra Hoekzema; Evan E Eichler; Raphael A Bernier
Journal:  Child Health Care       Date:  2020-03-17

2.  Altered gut microbial profile is associated with abnormal metabolism activity of Autism Spectrum Disorder.

Authors:  Zhou Dan; Xuhua Mao; Qisha Liu; Mengchen Guo; Yaoyao Zhuang; Zhi Liu; Kun Chen; Junyu Chen; Rui Xu; Junming Tang; Lianhong Qin; Bing Gu; Kangjian Liu; Chuan Su; Faming Zhang; Yankai Xia; Zhibin Hu; Xingyin Liu
Journal:  Gut Microbes       Date:  2020-04-21

3.  A molecular biomarker for prediction of clinical outcome in children with ASD, constipation, and intestinal inflammation.

Authors:  Stephen J Walker; Carl D Langefeld; Kip Zimmerman; Marshall Z Schwartz; Arthur Krigsman
Journal:  Sci Rep       Date:  2019-04-12       Impact factor: 4.379

4.  Vocal and motor behaviors as a possible expression of gastrointestinal problems in preschoolers with Autism Spectrum Disorder.

Authors:  Margherita Prosperi; Elisa Santocchi; Filippo Muratori; Chiara Narducci; Sara Calderoni; Raffaella Tancredi; Maria Aurora Morales; Letizia Guiducci
Journal:  BMC Pediatr       Date:  2019-11-29       Impact factor: 2.125

Review 5.  Dietary Fat Effect on the Gut Microbiome, and Its Role in the Modulation of Gastrointestinal Disorders in Children with Autism Spectrum Disorder.

Authors:  Monia Kittana; Asma Ahmadani; Farah Al Marzooq; Amita Attlee
Journal:  Nutrients       Date:  2021-10-27       Impact factor: 5.717

6.  Saliva RNA Biomarkers of Gastrointestinal Dysfunction in Children With Autism and Neurodevelopmental Disorders: Potential Implications for Precision Medicine.

Authors:  David Q Beversdorf; Kristin Sohl; David Levitskiy; Priscilla Tennant; Robin P Goin-Kochel; Rebecca C Shaffer; Alexandra Confair; Frank A Middleton; Steven D Hicks
Journal:  Front Psychiatry       Date:  2022-01-20       Impact factor: 4.157

7.  Constipation in autistic people and people with learning disabilities.

Authors:  Christina Maslen; Rebecca Hodge; Kim Tie; Richard Laugharne; Kirsten Lamb; Rohit Shankar
Journal:  Br J Gen Pract       Date:  2022-06-30       Impact factor: 6.302

  7 in total

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