| Literature DB >> 29863323 |
Marc Aixalà1, Rafael G Dos Santos1,2,3, Jaime E C Hallak2,3, José Carlos Bouso1.
Abstract
In the past decade, an increasing number of clinical trials are reporting evidence that psychedelics or serotonergic hallucinogens (such as lysergic acid diethylamide, psilocybin, and ayahuasca/dimethyltryptamine) could be effective in the treatment of mood, anxiety, and substance use disorders. The mechanisms responsible for these effects are not fully understood but seem to involve changes in bran dynamics in areas rich in serotonergic 5-HT2A receptors and in personality. In the present text, we present a brief and critical overview of the current research in this field, pointing out both promises and limitations of these studies.Entities:
Keywords: Psychedelics; anxiety; hallucinogens; mood; personality; substance abuse
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Year: 2018 PMID: 29863323 DOI: 10.1021/acschemneuro.8b00237
Source DB: PubMed Journal: ACS Chem Neurosci ISSN: 1948-7193 Impact factor: 4.418