L Ye1, Z Wang2, Z Li3, C Lv1, M-Q Man4. 1. Dalian Skin Disease Hospital, Dalian, Liaoning, China. 2. Department of Dermatology, The 7th People's Hospital of Shenyang City, Shenyang, Liaoning, China. 3. Department of Dermatology, The 2nd Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. 4. Dermatology Services, Veterans Affair Medical Center and University of California, San Francisco, CA, USA.
Abstract
BACKGROUND: Measurements of transepidermal water loss (TEWL) and stratum corneum (SC) hydration are important for assessing epidermal functions. However, the availability of reliable and user-friendly devices, which can simultaneously measure both TEWL and SC hydration and can allow health providers to remotely access data in time, is limited. MATERIALS AND METHODS: GPSkin Barrier® was compared with MPA5 system in the measurements of TEWL and SC hydration on the cheek, the dorsal hand, and the forearm in 200 normal volunteers, including 126 females and 74 males, aged 1-78 years with an average age of 45.24 ± 1.04 years. Correlation of data measured with MPA5 system and GPSkin Barrier® was determined. RESULTS: Levels of both TEWL and SC hydration measured with the Barrie GPSkin Barrier® were lower than that with MPA5 system on all 3 body sites except for hydration on the cheek. The levels of both TEWL and SC hydration measured with GpSkin Barrier® were correlated well with that measured with MPA5 system on all 3 body sites CONCLUSIONS: GPSkin Barrier® is a reliable, affordable, and versatile device for assessing epidermal permeability barrier function and SC hydration.
BACKGROUND: Measurements of transepidermal water loss (TEWL) and stratum corneum (SC) hydration are important for assessing epidermal functions. However, the availability of reliable and user-friendly devices, which can simultaneously measure both TEWL and SC hydration and can allow health providers to remotely access data in time, is limited. MATERIALS AND METHODS: GPSkin Barrier® was compared with MPA5 system in the measurements of TEWL and SC hydration on the cheek, the dorsal hand, and the forearm in 200 normal volunteers, including 126 females and 74 males, aged 1-78 years with an average age of 45.24 ± 1.04 years. Correlation of data measured with MPA5 system and GPSkin Barrier® was determined. RESULTS: Levels of both TEWL and SC hydration measured with the Barrie GPSkin Barrier® were lower than that with MPA5 system on all 3 body sites except for hydration on the cheek. The levels of both TEWL and SC hydration measured with GpSkin Barrier® were correlated well with that measured with MPA5 system on all 3 body sites CONCLUSIONS: GPSkin Barrier® is a reliable, affordable, and versatile device for assessing epidermal permeability barrier function and SC hydration.
Authors: Surabhi R Madhvapathy; Heling Wang; Jessy Kong; Michael Zhang; Jong Yoon Lee; Jun Bin Park; Hokyung Jang; Zhaoqian Xie; Jingyue Cao; Raudel Avila; Chen Wei; Vincent D'Angelo; Jason Zhu; Ha Uk Chung; Sarah Coughlin; Manish Patel; Joshua Winograd; Jaeman Lim; Anthony Banks; Shuai Xu; Yonggang Huang; John A Rogers Journal: Sci Adv Date: 2020-12-04 Impact factor: 14.136
Authors: Trinidad Montero-Vilchez; Carlos Cuenca-Barrales; Juan-Angel Rodriguez-Pozo; Pablo Diaz-Calvillo; Jesús Tercedor-Sanchez; Antonio Martinez-Lopez; Alejandro Molina-Leyva; Salvador Arias-Santiago Journal: Life (Basel) Date: 2022-01-17